Results 41 to 50 of about 363,391 (271)

Bevel-Tip Needle Deflection Modeling, Simulation, and Validation in Multi-Layer Tissues [PDF]

open access: yesarXiv, 2023
Percutaneous needle insertions are commonly performed for diagnostic and therapeutic purposes as an effective alternative to more invasive surgical procedures. However, the outcome of needle-based approaches relies heavily on the accuracy of needle placement, which remains a challenge even with robot assistance and medical imaging guidance due to ...
arxiv  

Fast Prototyping and Ex Vivo Evaluation of Dissolvable Millineedle Patches Made by Solvent Casting from CO2 Laser Ablated Elastomer Molds

open access: yesAdvanced Materials Interfaces, EarlyView.
CO2 laser ablation, a fast, inexpensive, and reproducible method, is used to create flexible elastomer molds with millimeter‐long cavities for the fabrication of dissolvable polymer needles. Made from PVP, these milli‐needles achieve ≈560 µm penetration into porcine skin, demonstrating their potential for effective transdermal drug delivery.
Matteo Tollemeto   +7 more
wiley   +1 more source

Computer-aided hepatic tumour ablation [PDF]

open access: yesLecture notes in computer science (LNCS) 2208 (2001) 1145-1146, 2006
Surgical resection of hepatic tumours is not always possible. Alternative techniques consist in locally using chemical or physical agents to destroy the tumour and this may be performed percutaneously. It requires a precise localisation of the tumour placement during ablation.
arxiv  

Controlling the Error on Target Motion through Real-time Mesh Adaptation: Applications to Deep Brain Stimulation [PDF]

open access: yes, 2017
We present an error-controlled mesh refinement procedure for needle insertion simulation and apply it to the simulation of electrode implantation for deep brain stimulation, including brain shift. Our approach enables to control the error in the computation of the displacement and stress fields around the needle tip and needle shaft by suitably ...
arxiv   +1 more source

In vivo Terahertz Sensing of Skin Cancer Patients

open access: yesAdvanced Photonics Research, EarlyView.
This study presents the first in vivo measurements of skin cancer patients in a hospital setting using a handheld THz probe. Furthermore, a new analysis approach is developed to generate a patient‐normalized THz response function, which enables clear contrast to be seen between cancer and healthy skin of the same patient.The first in vivo study of skin
Jacob J. Young   +4 more
wiley   +1 more source

Development of a patient-specific finite element model of the Transcatheter Aortic Valve Implantation (TAVI) procedure [PDF]

open access: yesarXiv, 2019
This work reports on a study to develop a patient-specific finite element model of the Transcatheter Aortic Valve Implantation procedure, using a model of a balloon-expandable percutaneous prosthetic aortic valve as a framework for the prediction of its performance.
arxiv  

3D Fusion between Fluoroscopy Angiograms and SPECT Myocardial Perfusion Images to Guide Percutaneous Coronary Intervention [PDF]

open access: yesarXiv, 2020
Background. Percutaneous coronary intervention(PCI) in stable coronary artery disease(CAD) is commonly triggered by abnormal myocardial perfusion imaging(MPI). However, due to the possibilities of multivessel disease and variability of coronary artery perfusion distribution, opportunity exists to better align anatomic stenosis with perfusion ...
arxiv  

The CNN-based Coronary Occlusion Site Localization with Effective Preprocessing Method [PDF]

open access: yes, 2019
The Coronary Artery Occlusion (CAO) acutely comes to human, and it highly threats the human's life. When CAO detected, Percutaneous Coronary Intervention (PCI) should be conducted timely. Before PCI, localizing the CAO is needed firstly, because the heart is covered with various arteries.
arxiv   +1 more source

Enhancing Nonenzymatic Glucose Detection Through Cobalt‐Substituted Hafnia

open access: yesAdvanced Science, EarlyView.
Proposed nonenzymatic glucose sensor utilizes ultrathin hafnia films engineered with cobalt and oxygen vacancies, grown via chemical solution deposition. Cobalt atoms with multivalent state act as sites of oxidation for glucose and oxygen vacancies enhance charger transfer, allowing precise glucose oxidation with minimal interference from other ...
Jeonghyeon Oh   +10 more
wiley   +1 more source

Artesunate Inhibits Neointimal Hyperplasia by Promoting IRF4 Associated Macrophage Polarization

open access: yesAdvanced Science, EarlyView.
This study shows that macrophage interferon regulatory factor 4 (IRF4) improved arterial injury‐induced neointimal hyperplasia by promoting of M2 polarization via up‐regulating krüppel‐like factor 4 (KLF4) in rodent and nonhuman primate models. Notably, artesunate is identified as a potent inducer of IRF4 in macrophages, and proposed as a promising ...
Jinlin Miao   +15 more
wiley   +1 more source

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