Results 91 to 100 of about 84,386 (305)

Multifunctional Gold Nanocluster‐Based PROTAC System for Targeted Degradation of Phosphorylated Tau and Modulation of Neuroinflammation in Alzheimer's Disease

open access: yesAdvanced Functional Materials, EarlyView.
We present a novel proteolysis‐targeting chimera (PROTAC) system conjugated to lipoic acid gold nanoclusters (PLANC), designed to degrade pTau, regulate inflammatory signaling, and effectively traverse the blood‐brain barrier (BBB). PLANC degraded pTau at various phosphorylation sites, with mechanistic studies confirming proteasome‐mediated degradation
Sarah Nevins   +9 more
wiley   +1 more source

Some curvature properties of perfect fluid spacetimes

open access: yes
In this paper we assume that a perfect fluid is the source of the gravitational field while analyzing the solutions to the Einstein field ...
De, Krishnendu   +2 more
core   +1 more source

Solitonic perturbations of perfect fluid Friedmann-Robertson-Walker cosmological models

open access: yes, 1987
The authors give a prescription for the application of the inverse scattering generation technique of Belinskii and Zakharov (1978,1979) to perfect fluid cosmological seed solutions in the context of a five-dimensional Kaluza-Klein formalism.
Diaz, M. C.   +2 more
core   +1 more source

A structure theorem for stationary perfect fluids [PDF]

open access: yesClassical and Quantum Gravity, 2005
It is proven that, under mild physical assumptions, an isolated stationary relativistic perfect fluid consists of a finite number of cells fibred by invariant annuli or invariant tori. For axially symmetric circular flows it is shown that the fluid consists of cells fibred by rigidly rotating annuli or tori.
openaire   +2 more sources

Packed for Ossification: High‐Density Bioprinting of hPDC Spheroids in HAMA Toward Endochondral Ossification

open access: yesAdvanced Healthcare Materials, EarlyView.
Human periosteum‐derived cell spheroids bioprinted at high density within a hyaluronic acid matrix promote fusion and hypertrophic cartilage formation in vitro. Early encapsulation enhances spheroid interaction and matrix maturation, generating scalable cartilage templates intended for endochondral bone regeneration.
Ane Albillos Sanchez   +6 more
wiley   +1 more source

Convective instability and transient growth in flow over a backward-facing step [PDF]

open access: yes, 2008
Transient energy growths of two- and three-dimensional optimal linear perturbations to two-dimensional flow in a rectangular backward-facing-step geometry with expansion ratio two are presented.
Sherwin, SJ   +8 more
core   +1 more source

Gravitational perfect fluid collapse in Gauss–Bonnet gravity

open access: yesEuropean Physical Journal C: Particles and Fields, 2017
The Einstein Gauss–Bonnet theory of gravity is the low-energy limit of heterotic super-symmetric string theory. This paper deals with gravitational collapse of a perfect fluid in Einstein–Gauss–Bonnet gravity by considering the Lemaitre–Tolman–Bondi ...
G. Abbas, M. Tahir
doaj   +1 more source

Functional Blood‐Brain Barrier Crossing by Biomimetic M13 Phage Vectors for Targeted Neuronal Delivery

open access: yesAdvanced Healthcare Materials, EarlyView.
This study investigates the M13 bacteriophage as a biomimetic nanovector capable of crossing in vitro models of the blood–brain barrier. By exploiting peculiar transcellular pathways, M13 avoids lysosomal degradation and preserves its structural integrity and functionality.
Silvia Vercellino   +12 more
wiley   +1 more source

Static perfect fluid cylinders

open access: yes, 1998
The field equations for cylindrically symmetric perfect fluid models with a non-scale invariant equation of state where the energy density is linearly related to the pressure are rewritten as a set of first order coupled ordinary differential equations ...
Claes Uggla   +5 more
core   +1 more source

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