Results 131 to 140 of about 520,977 (330)
NDST3‐Induced Epigenetic Reprogramming Reverses Neurodegeneration in Parkinson's Disease
Advanced Science, EarlyView.NDST3‐mediated epigenetic reprogramming revitalizes neuronal circuits in the substantia nigra and striatum to halt dopaminergic neuron degeneration and restore motor function in Parkinson's disease models. This strategy promotes neuronal maintenance and functional recovery, highlighting NDST3's therapeutic potential in neurodegenerative disorders ...
Yujung Chang +18 more
wiley +1 more source
Some classes of Trivially Perfect Graphs
, 2021 Ganesh Gandal, R. Mary Jeya Jothi
openalex +1 more source
Journal of Combinatorial Theory, Series B, 1990 A colouring of the vertices of a graph is said to be locally perfect if for each vertex x the neighbourhood N(x) of x is coloured by a number of colours which is equal to the cardinality of a maximum clique in N(x). The locally perfect graphs are those graphs for which any subgraph has a locally perfect colouring. It is shown in this paper that locally
openaire +2 more sources
Advanced Science, EarlyView.Diabetic bone marrow exhibits pathological ECM hyperviscosity that activates TRPV2‐mediated Ca2⁺ influx, leading to perinuclear F‐actin disassembly, nuclear deformation, and chromatin condensation. This cytoskeletal‐nuclear decoupling suppresses osteogenic differentiation of BMSCs.
Yao Wen +8 more
wiley +1 more source
Advanced Science, EarlyView.This study shows anti‐CEACAM5 CAR T‐cells are ineffective against colorectal cancer (CRC) because of CEACAM5 sequestration at intercellular junctions and the thick tumour cell glycocalyx. Enzymatic treatments of CRC cell monolayer/tissue section with trypsin or hyaluronidase restore CEACAM5 availability, enhance CAR T‐cell activation, increase ...
Debasis Banik +13 more
wiley +1 more source
The Expected Number of Perfect Matchings in Cubic Planar Graphs
, 2021 Marc Noy, Clément Requilé, Juanjo Rué
openalex +2 more sources
Advanced Science, EarlyView.Tumor evolution in lung adenocarcinoma is shaped by genetic alterations and spatial immune dynamics. By integrating whole‐exome sequencing, imaging mass cytometry, and spatial transcriptomics across two mouse models, this study reveals how mutational burden, immune infiltration, and cell–state interactions evolve during early and late carcinogenesis ...
Bo Zhu +34 more
wiley +1 more source
Finding all the perfect matchings in bipartite graphs
, 1994 K. Fukuda, Tomomi Matsui
openalex +2 more sources
Asymptotic enumeration of perfect matchings in $m$-barrel fullerene graphs [PDF]
, 2017 Afshin Behmaram, Cédric Boutillier
openalex +1 more source
Endocytic Control of Cell‐Autonomous and Non‐Cell‐Autonomous Functions of p53
Advanced Science, EarlyView.NUMB Ex3‐containing isoforms localize to the plasma membrane, where they recruit p53 through SNX9 and direct it to multivesicular bodies and exosomes. Exported p53 is taken up by neighboring cells and activates nuclear programs, revealing an intercellular, exosome‐based pathway that might help establish a tumor‐suppressive microenvironment.
Roberta Cacciatore +20 more
wiley +1 more source