Results 181 to 190 of about 783,181 (348)

Temporal Trajectories of the Tau Aggregate Interactome Reveal Stage‐Specific Vulnerabilities in Alzheimer's Disease

open access: yesAdvanced Science, EarlyView.
Tau populations with different aggregation states associate with distinct sets of proteins in the Alzheimer's disease brain. Proteomic discovery combined with single‐molecule analysis in neurons reveals dynamic associations involving proteostasis, metabolism and RNA biology.
Dorothea Böken   +8 more
wiley   +1 more source

Machine learning-based regression analysis of cyclopentane and cyclohexane molecular graphs. [PDF]

open access: yesSci Rep
Irfan M   +6 more
europepmc   +1 more source

Liquid‐Metal Interfacial Chemistry for Crystal and Defect Engineering in Two‐Dimensional Post‐Transition‐Metal Materials

open access: yesAdvanced Science, EarlyView.
Liquid‐metal interfaces provide dynamic reaction environments in which crystal growth, composition, and defect formation are intrinsically coupled. This Review reveals how interfacial oxidation, alloy thermodynamics, elemental migration, atmosphere, and processing govern defects in 2D post‐transition‐metal materials, and how these defects can be ...
Zhejun Hong   +7 more
wiley   +1 more source

PrOMet: Accurate and Robust Metal‐Binding Site and Type Prediction

open access: yesAdvanced Science, EarlyView.
PrOMet is a two‐stage deep learning framework for jointly predicting metal‐binding sites and ion identities from protein structures. Surface candidate sites are first pruned, followed by refinement of the most probable sites and metal types. This hierarchical strategy enables robust and accurate metal prediction for cryo‐EM and AlphaFold‐derived ...
Gangeun Park, Chaok Seok, Hahnbeom Park
wiley   +1 more source

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