Results 51 to 60 of about 82,260 (291)

Small RNA pathways in mammalian oocytes

open access: yesFEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

Great Shaykh Muhyiddin Ibn Arabi's Theory of Perfect Man

open access: yesThe Islamic Culture, 2017
In this Article, I have studied Ibn'Arabi's theory of Perfect Man. Because Ibn Arabi thinks that men have forgotten his past which was very glorious. The decline of Muslims position was very painful for Shaykh Akbar. He thinks every man can not be called
Muhammad Ahmed Qadri, Nazra Sultana
doaj  

Heart and Its Properties from Ibn Arabī’s Viewpoint [PDF]

open access: yesادبیات عرفانی, 2011
The truth of Human being according to Ibn Arabī is heart (qalb) that enslaves all man's inner and outer potentialities. Heart is the perfect manifestation of God with all its attributes, such as the First and the Last, the Apparent and the Hidden. As God
Morteza Shajari
doaj   +1 more source

Value of MRI Outcomes for Preventive and Early‐Stage Trials in Spinocerebellar Ataxias 1 and 3

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To examine the value of MRI outcomes as endpoints for preventive and early‐stage trials of two polyglutamine spinocerebellar ataxias (SCAs). Methods A cohort of 100 participants (23 SCA1, 63 SCA3, median Scale for the Assessment and Rating of Ataxia (SARA) score = 5, 42% preataxic, and 14 gene‐negative controls) was scanned at 3T up ...
Thiago J. R. Rezende   +26 more
wiley   +1 more source

"The concept of perfect man in manichaeism and Ibn 'Arabi's Doctrine" [PDF]

open access: yes, 2015
Gnosticism is a religious tradition based on transcendence reached by intuitive\ud means. The esoteric and practical wisdom of Gnosticism, which consists of inner\ud purification and asceticism, has had a deep influence on many religions, including\ud ...
Gachpazian, Samaneh
core   +2 more sources

Onasemnogene Abeparvovec in Type I Spinal Muscular Atrophy: 24‐Month Follow‐Up From the Italian Registry

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Onasemnogene abeparvovec (OA) is an AAV9‐based gene therapy for spinal muscular atrophy type I (SMA I). Real‐world outcomes show increased response variability compared to clinical trials, and follow‐up data beyond 12–18 months are limited.
Marika Pane   +43 more
wiley   +1 more source

Screening Routine Clinical Notes for Epilepsy Surgery Candidates Using Large Language Models

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Epilepsy surgery is severely underutilized despite proven efficacy, with substantial under‐referral of eligible patients in routine clinical practice. This study evaluated the potential role of large language models (LLMs) as decision‐support tools for screening unstructured clinical notes to identify epilepsy surgery candidates and ...
Uriel Fennig   +9 more
wiley   +1 more source

Plasma EV Proteomics Identifies ECM Remodeling and Inflammatory Proteins LUM and C7 as Candidate Biomarkers in FSHD

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit   +11 more
wiley   +1 more source

Uncovering G Protein‐Coupled Receptors: Novel Targets and Biomarkers for Predicting Glioma Prognosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Low‐grade gliomas (LGG) exhibit significant heterogeneity and recurrence risk. G protein‐coupled receptors (GPCR) contribute to glioma malignant progression, but their prognostic value remains unclear. This work attempts to formulate a GPCR‐based outcome‐predicting model for LGG. Methods Based on TCGA LGG data, the enrichment scores
Jun Yang   +4 more
wiley   +1 more source

The Role and Impact of Social Networks in our Lives [PDF]

open access: yesInternational Multidisciplinary Journal of Pure Life, 2016
Man is a perfect being who is perfect, thinking, and able to communicate, created by the Almighty and the Almighty Creator. Through communication, people communicate their ideas, express their needs, express themselves, and most importantly, influence ...
Elahe Nasirova (Azerbaijan)
doaj   +1 more source

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