Results 291 to 300 of about 18,418 (330)
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Perfluorocarbon-based antidiabetic agents
Journal of Medicinal Chemistry, 1992In a preliminary communication (J. Med. Chem. 1989, 32, 11-13) a series of perfluoro-N-[4-(1H-tetrazol-5ylmethyl)phenyl]alkana mides (perfluoro anilides I), designed as novel analogues of ciglitazone, were reported to possess oral antidiabetic activity in two genetic animal models of non-insulin-dependent diabetes mellitus (NIDDM): obese (ob/ob) and ...
K L, Kees +7 more
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Transabdominal oxygenation using perfluorocarbons
Journal of Pediatric Surgery, 1999Evaluation of the intraabdominal (intraperitoneal and intraluminal) administration of oxygen-saturated perfluorocarbon on both portal and arterial blood oxygenation.Eight male rabbits were divided into the test (n = 5) and control (n = 3) groups. Each underwent intrajejunal, intraperitoneal, and intravascular (artery, portal vein) catheter placements ...
T, Chiba +5 more
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Modified haemoglobins and perfluorocarbons
Current Opinion in Anaesthesiology, 1999After decades of research activities and product improvements in the field of artificial oxygen carriers based on either haemoglobin modifications or perfluorocarbon emulsions, these products have reached a critical stage of their development. Varieties of haemoglobin-based oxygen carriers and perfluorocarbon emulsions are under current clinical ...
K F, Waschke, T, Frietsch
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Arthrography Using Perfluorocarbon Compounds
Investigative Radiology, 1981The neat liquid and an emulsion of two perfluorocarbon compounds were injected into the knee joints of dogs and a human cadaver to investigate their applicability for arthrography. Excellent delineation of joint structures was observed for as long as 24 hours, but after 24 hours each contrast agent leaked out of the joint capsule into surrounding ...
D R, Enzmann, S, Young
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Perfluorocarbon liquids in ophthalmology
Survey of Ophthalmology, 1995Perfluorocarbon liquids have been used to facilitate surgery in a wide variety of conditions, including proliferative vitreoretinopathy, giant retinal tears, drainage of suprachoroidal hemorrhages, diabetic traction, retinal detachments with a rhegmatogenous component, dislocated crystalline or intraocular lenses, and retinal detachment associated with
Steven G. Kramer +4 more
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Perfluorocarbon-associated gas exchange
Critical Care Medicine, 1991Liquid ventilation with oxygenated perfluorocarbon eliminates surface tension due to pulmonary air/fluid interfaces, and improves pulmonary function and gas exchange in surfactant deficiency. In liquid ventilation, perfluorocarbon is oxygenated, purged of CO2, and cycled into and out of the lungs using an investigational device.
B P, Fuhrman +2 more
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Perfluorocarbons attenuate oxidative lung damage
Pediatric Pulmonology, 2003AbstractThe aim of this study was to investigate the effect of tidal liquid ventilation (TLV) compared to conventional mechanical ventilation (CMV) on oxidative lung damage in the setting of acute respiratory distress syndrome (ARDS). After repeated lung lavages, 10 minipigs were treated with CMV or TLV for 4 hr before the animals were sacrificed ...
C. DANI +9 more
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Perfluorocarbons as blood substitutes
Annals of Emergency Medicine, 1986The development of perfluorocarbon (PFC) solutions as clinically useful oxygen-carrying agents has been a slow process because PFC is immiscible in aqueous solutions, including blood. Therefore, it has been necessary to develop emulsions for IV infusions.
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