Results 81 to 90 of about 29,810 (206)

Bayesian evaluation of a physiologically based pharmacokinetic (PBPK) model for perfluorooctane sulfonate (PFOS) to characterize the interspecies uncertainty between mice, rats, monkeys, and humans: Development and performance verification

Environment International, 2019
A challenge in the risk assessment of perfluorooctane sulfonate (PFOS) is the large interspecies differences in its toxicokinetics that results in substantial uncertainty in the dosimetry and toxicity extrapolation from animals to humans. To address this
Wei-Chun Chou, Zhoumeng Lin
doaj   +1 more source

A Hexadecacationic Metal–Organic Cage for Anchoring Sulfonates: High‐Order Binding of Di‐ and Trisulfonates and High‐Performance Removal of Perfluorosulfonates from Water

Advanced Science
Developing synthetic hosts capable of binding sulfonate anions or sequestering perfluorosulfonates is highly important. In this work, the self‐assembly of a tripyridinium‐tricarboxylate ligand with Cp2ZrCl2 (Cp = η5‐C5H5) is reported, yielding a highly ...
Yawei Liu, Gen Li, Xiang Zhang, Zelin Du, Tingting Zhang, Yongya Zhang, Roy Lavendomme, En‐Qing Gao, Dawei Zhang   +8 more
doaj   +1 more source

Sesamin ameliorates perfluorooctane sulfonate-induced myocardial injury by inhibiting apoptosis and autophagy in mice

Ecotoxicology and Environmental Safety
Background: Perfluorooctane sulfonate (PFOS) is a ubiquitous, persistent organic pollutant known to elicit significant cardiotoxicity, with no effective clinical treatments currently available.
Siqi Zhu, Yadong Zhang, Hao Tian, Shenghe Li, Chongyue Zhang, Xiaolong Zhang, Huanting Pei, Ziqian Zeng, Jingyi Ren, Yuxia Ma   +9 more
doaj   +1 more source

Estimation of PFOS emission from domestic sources in the eastern coastal region of China

Environment International, 2013
Perfluorooctane sulfonate (PFOS) and related chemicals (collectively “PFOS equivalents”) have been released to the environment through widespread consumer use and disposal of PFOS-containing products like carpet, leather, textiles, paper, food containers,
Shuangwei Xie, Yonglong Lu, Tieyu Wang, Shijie Liu, Kevin Jones, Andy Sweetman   +5 more
doaj   +1 more source

Protein Profiles in Zebrafish (Danio rerio) Embryos Exposed to Perfluorooctane Sulfonate

, 2009
Perfluorooctane sulfonate (PFOS) is widely distributed and persistent in the environment and in wildlife, and it has the potential for developmental toxicity. However, the molecular mechanisms that lead to these toxic effects are not well known.
Zhou, Bingsheng, Yeung, Leo W. Y., Wu, Rudolf S. S., Shi, Xiongjie, Zhou, BS, Chinese Acad Sci, Inst Hydrobiol, State Key Lab Freshwater Ecol & Biotechnol, Wuhan 430072, Peoples R China, Lam, Paul K. S.   +5 more
core  

Single-cell RNA sequencing reveals the role of mitochondrial dysfunction in the cardiogenic toxicity of perfluorooctane sulfonate in human embryonic stem cells

Ecotoxicology and Environmental Safety
Perfluorooctane sulfonate (PFOS), an endocrine-disrupting chemical pollutant, affects embryonic heart development; however, the mechanisms underlying its toxicity have not been fully elucidated.
Min Qiu, Jing Chen, Mingqin Liu, Zhiqiang Nie, Miaola Ke, Guanghui Dong, Haishan Zhao, Chengbin Zhou, Haiyan Zeng, Biaochuan He, Jimei Chen, Jian Zhuang, Xiaohong Li, Yanqiu Ou   +13 more
doaj   +1 more source

The Aryl Hydrocarbon Receptor Mediates the Neurodevelopmental Toxicity of Perfluorooctane Sulfonamide in Zebrafish Larvae

Toxics
Perfluorooctane sulfonamide (PFOSA), the direct precursor to perfluorooctane sulfonate (PFOS), is widely present in the environment. Research has indicated that PFOSA is cardiotoxic and hepatotoxic, but its impact on neurodevelopment remains unclear.
Pinyi Chen, Kang Wang, Jie Zhang, Yan Jiang, Tao Chen   +4 more
doaj   +1 more source

Reductive Defluorination of Perfluorooctane Sulfonate

, 2016
Perfluorooctane sulfonate (PFOS) is under increased scrutiny as an environmental pollutant due to recent reports of its worldwide distribution, environmental persistence, and bioaccumulation potential.
Vicki H. Wysocki (1235367), Valeria Ochoa-Herrera (2441047), Neil E. Jacobsen (477784), Jim A. Field (1414387), Reyes Sierra-Alvarez (1414393), Arpad Somogyi (1624348)   +5 more
core   +1 more source

PFOS Impairs Cognitive Function in Female Rats by Disrupting Astrocyte-Derived Estrogen–ERβ–NDRG2 Signaling Axis

Toxics
Epidemiological investigations have indicated that females are particularly susceptible to perfluorooctane sulfonate (PFOS)-induced cognitive impairment, yet the mechanisms underlying this sex-specific vulnerability remain obscure.
Yue Su, Xiyang You, Zongqin Wang, Yufeng Tan, Jing Shao, Xiaohui Liu   +5 more
doaj   +1 more source

Bland Altman plot for perfluorooctane sulfonate after transformation by the natural logarithm, stratified by season.

, 2015
The first plot represents samples from the winter, while the second plot represents samples from the summer. The average lnPFOS is the average of the natural log-transformed concentrations of perfluorooctane sulfonate (PFOS) in the transported and ...
Cathrine Carlsen Bach (793963), Tine Brink Henriksen (332160), Jørn Olsen (60072), Jens Fuglsang (793965), Rossana Bossi (793964), Ellen Aagaard Nohr (205289), Bodil Hammer Bech (417436)   +6 more
core   +1 more source