Aims Predetermined treatment duration limits (PTDLs) are often used by Taiwan's National Health Insurance Administration to contain healthcare costs, but they may compromise patient outcomes. Therefore, we studied Taiwan's 2017 extension of the bevacizumab PTDL from 24 to 36 weeks in metastatic colorectal cancer (mCRC) to evaluate whether prolonged ...
Wei‐Ming Huang +6 more
wiley +1 more source
Merged gastrointestinal stromal tumor, intestinal obstruction, and perforation in Meckel's diverticulum: Case report. [PDF]
Gao Y, Hu F, Xia Y, Lv L.
europepmc +1 more source
Risk of gastrointestinal bleeding by specific SSRIs and SNRIs: A systematic review and meta‐analysis
Aim The purpose of this study is to estimate the risk of gastrointestinal bleeding (GIB) by selective serotonin reuptake inhibitors (SSRIs) and serotonin–norepinephrine reuptake inhibitors (SNRIs) individual agents. Methods A systematic review was conducted for each unique antidepressant (i.e.
Ainhoa Gomez‐Lumbreras +8 more
wiley +1 more source
Right Coronary Artery Perforation with Subsequent Graft Stent Embolization to the Left Main Coronary Artery: It Never Rains but It Pours! [PDF]
Yilmaz E, Karahan F, Kaya Ç, Yalta K.
europepmc +1 more source
Role of AS-OCT in assessment of healing of thin or perforated cornea treated by amniotic membrane graft and PRP clot. [PDF]
Khalafallah AM +4 more
europepmc +1 more source
We developed a cyclo‐RGD peptide‐conjugated antiferromagnetic nanoparticle (RANP) as a targeted T1 contrast agent. Under 9 T MRI conditions, RANP exhibited an r1 value of 1.88 mM−1 s−1 and a low r2/r1 ratio of 1.84, enabling the detection of esophageal tumors as small as 0.8 mm in vivo. Abstract Early, non‐invasive detection of esophageal cancer at sub‐
Wenkui Mo +15 more
wiley +1 more source
Microtopography enhances intestinal drug absorption via Piezo1‐mediated tight junction modulation
Microtopography‐driven enhancement of oral peptide drug delivery by activating Piezo1 channels significantly improves paracellular permeability and bioavailability, offering a novel approach for optimizing macromolecule absorption in pharmaceutical formulations.
Yu Hu +12 more
wiley +1 more source
A Race Against Rupture: Saving a Diabetic From Gallbladder Perforation. [PDF]
Murugesan P +2 more
europepmc +1 more source
Perforation peritonitis secondary to jejunal diverticulosis
K.C. Kapil Mani +5 more
openalex +2 more sources
Marine silicon for biomedical sustainability
Schematic illustrating marine silicon for biomedical engineering. Abstract Despite momentous divergence from oceanic origin, human beings and marine organisms exhibit elemental homology through silicon utilization. Notably, silicon serves as a critical constituent in multiple biomedical processes.
Yahui Han +3 more
wiley +1 more source

