Results 281 to 290 of about 400,764 (338)

Impact of extended insurance coverage on survival outcomes among patients with metastatic colorectal cancer in Taiwan

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims Predetermined treatment duration limits (PTDLs) are often used by Taiwan's National Health Insurance Administration to contain healthcare costs, but they may compromise patient outcomes. Therefore, we studied Taiwan's 2017 extension of the bevacizumab PTDL from 24 to 36 weeks in metastatic colorectal cancer (mCRC) to evaluate whether prolonged ...
Wei‐Ming Huang   +6 more
wiley   +1 more source

Risk of gastrointestinal bleeding by specific SSRIs and SNRIs: A systematic review and meta‐analysis

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aim The purpose of this study is to estimate the risk of gastrointestinal bleeding (GIB) by selective serotonin reuptake inhibitors (SSRIs) and serotonin–norepinephrine reuptake inhibitors (SNRIs) individual agents. Methods A systematic review was conducted for each unique antidepressant (i.e.
Ainhoa Gomez‐Lumbreras   +8 more
wiley   +1 more source

A targeted antiferromagnetic nanoprobe for ultra‐sensitive magnetic resonance imaging detection of sub‐millimeter esophageal tumors

open access: yesBMEMat, EarlyView.
We developed a cyclo‐RGD peptide‐conjugated antiferromagnetic nanoparticle (RANP) as a targeted T1 contrast agent. Under 9 T MRI conditions, RANP exhibited an r1 value of 1.88 mM−1 s−1 and a low r2/r1 ratio of 1.84, enabling the detection of esophageal tumors as small as 0.8 mm in vivo. Abstract Early, non‐invasive detection of esophageal cancer at sub‐
Wenkui Mo   +15 more
wiley   +1 more source

Microtopography enhances intestinal drug absorption via Piezo1‐mediated tight junction modulation

open access: yesBMEMat, EarlyView.
Microtopography‐driven enhancement of oral peptide drug delivery by activating Piezo1 channels significantly improves paracellular permeability and bioavailability, offering a novel approach for optimizing macromolecule absorption in pharmaceutical formulations.
Yu Hu   +12 more
wiley   +1 more source

Perforation peritonitis secondary to jejunal diverticulosis

open access: diamond
K.C. Kapil Mani   +5 more
openalex   +2 more sources

Marine silicon for biomedical sustainability

open access: yesBMEMat, EarlyView.
Schematic illustrating marine silicon for biomedical engineering. Abstract Despite momentous divergence from oceanic origin, human beings and marine organisms exhibit elemental homology through silicon utilization. Notably, silicon serves as a critical constituent in multiple biomedical processes.
Yahui Han   +3 more
wiley   +1 more source

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