Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
Energy efficient transport technology: Program summary and bibliography [PDF]
The Energy Efficient Transport (EET) Program began in 1976 as an element of the NASA Aircraft Energy Efficiency (ACEE) Program. The EET Program and the results of various applications of advanced aerodynamics and active controls technology (ACT) as ...
Bartlett, D. W. +2 more
core +1 more source
The perceptions and experience of developing patient (version of) guidelines: a descriptive qualitative study with Chinese guideline developers. [PDF]
BMC Health Serv Res, 2023 Yan L +8 more
europepmc +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Security Requirements of Internet of Things-Based Healthcare System: a Survey Study. [PDF]
Acta Inform Med, 2019 Nasiri S +3 more
europepmc +1 more source
Heightened consciousness and curriculum in a time of crisis. [PDF]
Prospects (Paris), 2021 Poindexter NK, Smith LG, Wang H.
europepmc +1 more source
PICALM::MLLT10 translocated leukemia
FEBS Letters, EarlyView.This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
Points of View and Readers' Immersion in Translation: A Neurocognitive Interpretation of Poetic Translatability. [PDF]
Front Psychol, 2022 Chen Q, Shen L, Ochs S, Xiao K.
europepmc +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
A 2021 Update on Syphilis: Taking Stock from Pathogenesis to Vaccines. [PDF]
Pathogens, 2021 Tiecco G +7 more
europepmc +1 more source