Organoids in pediatric cancer research
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Development of a new method for maintainability and downtime analysis of mining machinery. [PDF]
Dashtaki MR, Jafari AJ, Hoseinie SH.
europepmc +1 more source
Selection of Internal Standards for Quantitative Matrix-Assisted Laser Desorption/Ionization Mass Spectrometric Analysis Based on Correlation Coefficients. [PDF]
Yang S, Mu L, Feng R, Kong X.
europepmc +1 more source
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Lesion characteristics of long application time ablation using unipolar half-normal saline irrigation and bipolar normal saline irrigation. [PDF]
Kasai T +9 more
europepmc +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
A novel global health index framework for asset prognostics and health management in the oil and gas industry. [PDF]
Alfahdi K, Gultekin H, Summad E.
europepmc +1 more source
Petri-net-based 2D design of DNA walker circuits. [PDF]
Gilbert D, Heiner M, Rohr C.
europepmc +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Chiral Differentiation of Amino Acids by In-Source Collision-Induced Dissociation Mass Spectrometry. [PDF]
Kong X, Huo Z, Zhai W.
europepmc +1 more source

