Results 51 to 60 of about 35,129,579 (242)
Pediatric Idiopathic Multicentric Castleman Disease Is Often Severe But Responsive to Siltuximab
ABSTRACT Background Idiopathic multicentric Castleman disease (iMCD) is a potentially fatal immunologic disorder marked by widespread lymphadenopathy and inflammation. Siltuximab, an interleukin‐6 (IL‐6) inhibitor, is the only FDA‐approved treatment for adult patients with iMCD.
Bridget Austin +17 more
wiley +1 more source
Performance management at design actvity level [PDF]
The overriding aim of much of the engineering design research is to improve the performance of the design process, and consequently the product development process. Much has been written within the product development literature on the performance of the
Duffy, A.H.B., O'Donnell, F.J.
core +3 more sources
This research evaluates the seismic resilience of lifeline bridge columns in Vancouver, British Columbia, by comparing traditional reinforced concrete (RC) columns with an equivalent circular concrete-encased steel (CES) system.
Mohammadreza Kenarkoohi, Munzer Hassan
doaj +1 more source
ABSTRACT Background Numerous international studies have reported declines in new cancer diagnoses, delayed diagnoses and disruptions in cancer treatment following the implementation of COVID‐19 pandemic public health measures, raising concerns that these effects may ultimately contribute to increased cancer mortality.
Friederike Erdmann +8 more
wiley +1 more source
Devastating earthquakes across the globe have exposed the vulnerability of civil infrastructure, resulting in severe structural collapse, significant casualties, economic losses, and enduring societal impacts.
Madhu Beerabbi Eshapurada +1 more
doaj +1 more source
General Concerns Life-Cycle Design of Economical Ice-Resistant Structures in the Bohai Sea
In China, the oil and natural gas resources of Bohai Bay are mainly marginal oil fields. It is necessary to build both iceresistant and economical offshore platforms.
Zhang Da-yong +2 more
doaj +1 more source
Referral Patterns and Diagnostic Timeliness in Pediatric Cancer: A Hospital‐Based Study in Indonesia
ABSTRACT Background Timely diagnosis and treatment are critical for improving survival among children with cancer. In low‐ and middle‐income countries (LMICs), delays are common and may be influenced by fragmented referral pathways and diagnostic limitations.
Nur Melani Sari +5 more
wiley +1 more source
Review and application of engineering design models for building fire smoke movement and control
Since the 1970s, researchers have developed semi-empirical models to describe fire smoke movement inside buildings, but there are three major issues. Firstly, several plume models are available to estimate the smoke production rate and the capacity of ...
Mingchun Luo +3 more
doaj +1 more source
ABSTRACT Relapsed and/or refractory (R/R) pediatric acute leukemia carries a dismal prognosis, largely driven by chemoresistance to conventional salvage therapy. The BH3‐mimetic venetoclax, combined with chemotherapy or hypomethylating agents, has demonstrated efficacy in small clinical trials.
Katherine S. Colman +9 more
wiley +1 more source
ABSTRACT Background Latino children are projected to make up nearly one‐third of United States (US) children by 2060, and many of their caregivers speak Spanish. Prior survey research has documented communication difficulties for Spanish‐speaking caregivers of children with cancer, but contemporary qualitative data are limited.
Jenny Ruiz +6 more
wiley +1 more source

