Results 201 to 210 of about 20,833,504 (341)

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

open access: yesMolecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern   +7 more
wiley   +1 more source

CentrePiece Vol. 4 No. 2 [PDF]

open access: yes, 1999
Centre for Economic Performance,
core  

Costs of acute admitted patients in public hospitals from 2011–12 to 2013–14 [PDF]

open access: yes
Every day, decisions are made in hospitals, or by governments, that influence how efficiently hospitals run. In 2013–14, the running costs of public hospitals ($44 billion) continued to represent the largest proportion of the $154.6 billion that was ...
National Health Performance Authority
core  

Anthropometric Determinants of Rowing Performance in a Multinational Youth Cohort. [PDF]

open access: yesJ Funct Morphol Kinesiol
Suszter L   +4 more
europepmc   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

open access: yesMolecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici   +8 more
wiley   +1 more source

CentrePiece Vol. 15 No. 3 [PDF]

open access: yes, 2010
Centre for Economic Performance,
core  

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

open access: yesMolecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert   +13 more
wiley   +1 more source

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