Results 131 to 140 of about 617,802 (334)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Model Penilaian Kinerja Instruktur SMK Mikael Surakarta: Dalam Upaya Mempersiapkan Lulusan Siap Kerja [PDF]

open access: yes, 2012
Performance appraisal is a formal and structured system of measuring and assessing employees\u27 work performance using performance standards defined by organization.
Setiawaty, T. (Tutty)
core  

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Peranan Penilaian Prestasi Kerja Terhadap Kinerja Karyawan Pada PT Pos Indonesia (Persero) Kantor Wilayah USAha Pos III Palembang [PDF]

open access: yes, 2015
The research is concerning about the act of appraisal from employes performance at PT Post Indonesia (Persero) Kantor Wilayah Usaha Pos III Palembang. Becoming the object of this research is employes of PT Pos Indonesia (Persero) Kantor Wilayah Usaha ...
Al Hushori, Al Hushori   +1 more
core   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

The Use of Performance Appraisal Systems: Evidence from Dutch Establishment Data [PDF]

open access: yes, 2011
Using Dutch data, we examine the characteristics of establishments that operate performance appraisal systems. Our estimates provide a couple of interesting results: (1) Several indicators of multitasking are positively associated with the use of ...
Jirjahn, Uwe, Poutsma, Erik
core  

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