Results 121 to 130 of about 5,109,523 (285)

An analysis of final year student project performance in mechanical engineering [PDF]

, 2008
This paper describes a statistical analysis of the students' results in mechanical engineering Final Year Project (FYP) at undergraduate level eight. Project marks of the final year students obtained over the past six years (2002-2008) were recorded and ...
Brabazon, Dermot, Karazi, Shadi, Molloy, David, Smyth, Philip   +3 more
core  

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Strength-Dependent Differences in the Magnitude and Time Course of Post-Activation Performance Enhancement in High Jump Athletes

Journal of Functional Morphology and Kinesiology
Background: A post-activation performance enhancement (PAPE) can acutely improve explosive actions, but its time course may be influenced by individual strength levels.
Javier Sanchez-Sanchez, Alejandro Rodríguez-Fernández   +1 more
doaj   +1 more source

Using Performance Assessment to Empower Students' Learning Ownership and Promote Achievement in EFL Writing Courses [PDF]

, 2019
This study aims at investigating (1) To what extent performance assessment successfully fosters students' learning ownership and writing achievement and (2) Teachers' readiness related to the implementation of performance assessment in writing courses ...
Dewi, N. L. (N), Kusuma, I. P. (I), Marhaeni, A. A. (A), Paramartha, A. A. (A)   +3 more
core  

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

Framework for Evaluation of the IT&C Audit Metrics Impact [PDF]

The paper defines an assessment system for performance of IT&C audit process. The analytical models of performance indicators are provided together with the interpretation of their results.
Marius POPA
core  

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

Molecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard, Sarmad Mehmood, Eva Boysen Fynboe Ebert, Peter Meldgaard, Anindya Dutta, Boe S. Sorensen   +5 more
wiley   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

Correction Factor for Mitigating the ‘One-Size-Fits-All’ Phenomenon in Assessing Low-Carbon City Performance

Land
Performance assessment of low carbon cities (LCCs) attracts great interest and attention from academia, industry, and government as an effective measure to promote urban low-carbon development. However, the efforts of LCCs could be misinterpreted without
Shiju Liao, Liyin Shen, Xi Chen, Xiangrui Xu, Qingqing Wang, Ziwei Chen, Haijun Bao   +6 more
doaj   +1 more source