Results 241 to 250 of about 15,393,463 (311)

Hemorrhage Segmentation in Fundus Images Using the U-Net 3+ Model: Performance Comparison Across Retinal Regions. [PDF]

J Imaging Inform Med
Kang YH, Kim YJ, Kim KG.
europepmc   +1 more source

Optimization of seminal extracellular vesicle isolation protocols for cancer biomarker analysis using proteomic profiling

Molecular Oncology, EarlyView.
This paper shows that size‐exclusion chromatography and sequential centrifugation applied to seminal plasma enrich for different populations of extracellular vesicles. This may significantly affect the detection and analysis of extracellular vesicle‐associated cancer biomarkers.
Elen Telumyan, Beatriz Martín‐Gracia, Eva Bassols‐Citores, Krizia Sagini, Maria K. Andersen, Tuula A. Nyman, May‐Britt Tessem, Morten B. Rye, Alicia Llorente   +8 more
wiley   +1 more source

Addressing multicollinearity in general linear model: A novel approach for ridge parameter with performance comparison. [PDF]

PLoS One
Luqman M, Bhatti SH, Aydin D, Jamil M.
europepmc   +1 more source

Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy

Molecular Oncology, EarlyView.
We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley   +1 more source

Performance Comparison of the Prediction Models for Enteric Methane Emissions from Dairy Cattle. [PDF]

Vet Sci
Song M, Ren Y, Li Z, Dong R.
europepmc   +1 more source

Spatial heterogeneity of hotspot mutations and clonal relatedness in ovarian endometrioid carcinoma

Molecular Oncology, EarlyView.
Spatially resolved analysis revealed heterogeneous distributions of selected cancer‐associated mutations within ovarian endometrioid carcinomas. Shared mutations between paired endometrial and ovarian tumors supported clonal relatedness. These findings highlight the value of sampling multiple tumor regions when interpreting molecular profiles ...
Takahito Ashihara, Kosuke Murakami, Shiro Takamatsu, Akiko Kanto, Seiichi Mori, Tomoyuki Otani, Kazuko Sakai, Yasushi Kotani, Kazuto Nishio, Kaoru Abiko, Noriomi Matsumura   +10 more
wiley   +1 more source

Performance comparison of four exome capture platforms on DNBSEQ-Series high throughput sequencer. [PDF]

BMC Genomics
Li M, Yang X, Liang X, Jia Z, Zheng S, Zhang Y, Huang J, Liu P, Chen F.   +8 more
europepmc   +1 more source

The multifaceted roles of lysosomes in cancer

Molecular Oncology, EarlyView.
Lysosomes support cancer cell adaptation by integrating macromolecule degradation and nutrient recycling with nutrient sensing, inter‐organelle communication and immune regulation. These interconnected functions can promote tumour growth, stress tolerance and therapy resistance, while also creating context‐dependent vulnerabilities that may be ...
Jia Li, Kevin M. Ryan
wiley   +1 more source

Multiparametric performance comparison of dental composites for clear aligner attachments. [PDF]

BMC Oral Health
Guan Y, Xu J, Qiu J, Cai H, Xia W, Ye Z, Sang T.   +6 more
europepmc   +1 more source