Results 111 to 120 of about 3,037,170 (287)

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Análise de desempenho de sistemas de produção modais de pecuária de cria no Brasil Performance evaluation of livestock production systems in Brazil

open access: yesProduction, 2013
Neste artigo propõe-se analisar comparativamente o desempenho de sistemas de produção modais de pecuária extensiva de corte na fase de cria em 21 municípios brasileiros.
João Carlos Correia Baptista Soares de Mello   +4 more
doaj  

PICALM::MLLT10 translocated leukemia

open access: yesFEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen   +7 more
wiley   +1 more source

Dictating Aesthetic and Political Legitimacy through Golden Age Theater: Fuente Ovejuna at the Teatro Español, Directed by Cayetano Luca de Tena (1944)

open access: yes, 2018
Emboldened by their success in the Spanish Civil War (1936–1939), Nationalist ideologues sought to revitalize the stagnant Spanish theater and promote values associated with the newly formed authoritarian regime.
Oechler, Christopher C.
core  

Uso de procedimentos não cirúrgicos para a produção, recuperação e inovulação de embriões em pequenos ruminantes. [PDF]

open access: yes, 2019
O objetivo deste artigo foi descrever técnicas não cirúrgicas associadas à recuperação e inovulação de embriões em caprinos e ovinos. Os procedimentos relativos a estas etapas da produção in vivo de embriões destes animais foram descritos de forma ...
FONSECA, J. F. da   +2 more
core  

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Efeito da utilização de simbiótico e do sistema de criação sobre o desempenho e morfometria do epitélio gastrintestinal de frangos de corte tipo colonial = Effect of symbiotic use and production system on the performance and morphometrics of the intestinal epithelium of free-range broiler chickens

open access: yesActa Scientiarum: Animal Sciences, 2007
O objetivo deste estudo foi avaliar o desempenho e a morfometria do epitélio intestinal de frangos de corte da linhagem colonial Label Rouge, submetidos a dietas com e sem adição de simbiótico, e distribuídos em dois sistemas de criação, confinados e com
Augusto Balog Neto   +5 more
doaj  

Drama activities to enhance motivation and oral production in EF high school students from the province of Valparaíso, Chile : a quasi-experimental research [PDF]

open access: yes, 2018
Tesis (Pedagogía en Inglés)The importance of drama activities as a key element in the acquisition of a second language has been acknowledged by theorists and researchers of the area who consider this tool as an important factor to increase student’s ...
Albarrán Navarro, Viviana   +3 more
core  

Pilotage Souple de la Performance des Systèmes de Production

open access: yes, 2011
The two most recognized missions of a control system are the measurement of the performance achieved by the enterprise and its continuous improvement monitoring. However these prerogatives are no longer sufficient to ensure its overall efficiency. The strained climate in which the firm of nowadays evolves, does not leave any more room for trials and ...
openaire   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

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