Results 181 to 190 of about 6,335,595 (355)

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

Performance evaluation of an operational dengue forecasting system (D-MOSS) in Vietnam. [PDF]

PLOS Glob Public Health
Campbell AM, Colón-González F, Quoc DK, Tuan NH, Dong NT, Trang TT, Sulaiman LHB, Wong SF, Hofmann B, Tsarouchi G, Harpham Q, Nam VS, Brady O.   +12 more
europepmc   +1 more source

Analysis and performance evaluation of computation models for node localization in deep sea using UWSN [PDF]

Manni Kumar, Nitin Goyal, Ashutosh Kumar Singh, Rakesh Kumar, Arun Kumar Rana   +4 more
openalex   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Synthesis and Performance Evaluation of Polyamine Boron Crosslinker for Gel Fracturing Fluid. [PDF]

Gels
Wang Q, Dong T, Feng Q, Huang S, Zhang X, Jiang G.   +5 more
europepmc   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

Performance Evaluation and Oxide Layer Characterization of Self-Protective Cu/W-La2o3 Composite Electrodes Prepared by Gas Pressure Infiltration for Continuous Arcing in Air

Naďa Beronská, Marek Gebura, Tomáš Dvořák, Miroslav Čavojský, Zuzana Hájovská, P. Švec, P. Švec, Lukáš Karaffa, Eva Pospíšilová   +8 more
openalex   +1 more source

Haptic guides in cooperative virtual environments: Design and human performance evaluation

, 2010
Sehat Ullah, Paul Richard, Samir Otmane, Mickaël Naud, Malik Mallem   +4 more
openalex   +2 more sources

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Adaptation and performance evaluation of Perendale, Dorper, and Suffolksheep in Bangladesh. [PDF]

J Adv Vet Anim Res
Desha NH, Afrin S, Pasha MMH, Chawdhury MNH, Rahman MZ.   +4 more
europepmc   +1 more source