Results 81 to 90 of about 829,596 (216)

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

FEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Machine Learning-Based Prediction of Breast Cancer in Women: Insights From Feature Selection of Clinical and Lifestyle Data. [PDF]

Int J Breast Cancer
Allahqoli L, Behzadi MH, Aghamohammadi SZ, Hakimi S, Salehiniya H, Fallahi A, Rahmani A, Shahabinia Z, Mazidimoradi A, Momenimovahed Z, Ghiyasvand M.   +10 more
europepmc   +1 more source

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

FEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson, Tomáš Gedeon, Mauricio Garcia Benitez, Campbell Putnam, William R. Harcombe, Radhakrishnan Mahadevan, Ashley E. Beck   +6 more
wiley   +1 more source

Performance of Statistical and Machine Learning Risk Prediction Models for Advanced Breast Cancer. [PDF]

Cancer Epidemiol Biomarkers Prev
Chen S, Kerlikowske K, Su YR, Hubbard RA, Gard CC, Tice JA, Sprague BL, Ahern TP, Miglioretti DL.   +8 more
europepmc   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

Utilizing generative artificial intelligence to create simulated patient for history taking in gynecology. [PDF]

BMC Med Educ
Gao L, Zhang L, Zhang Y, Wu M, Xu J, Lu D.   +5 more
europepmc   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Performing Music History

Calenda, 2018
Music history is a matter of research, it is a matter of novels, films, comics or computer games. Also: Music history is subject matter to music theater. Performances of music history lie at the center of this conference: Be it André-Ernest-Modeste Grétry’s opera prologue “Les trois ages de l’opéra”, Hans Pfitzner’s opera “Palestrina” or Franz ...
openaire   +1 more source

Risk Factors and Development of a Risk Prediction Model for PICC-Related Thrombosis in Radiotherapy Inpatients: A Single-Center Retrospective Cohort Study. [PDF]

Risk Manag Healthc Policy
Lin QM, Guo QL, Lin ZB, Chen AY, Chen Z, Zhang QY, Chen LY, Lin BH.   +7 more
europepmc   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source