Steroid use and misuse: a key performance indicator in the management of IBD. [PDF]
Frontline Gastroenterol, 2021 Blackwell J +5 more
europepmc +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
More blastocysts are produced from fewer oocytes in ICSI compared to IVF - results from a sibling oocytes study and definition of a new key performance indicator. [PDF]
Reprod Biol Endocrinol, 2021 Chamayou S +10 more
europepmc +1 more source
The Role of the IFO Business Climate Indicator and Asset Prices in German Monetary Policy [PDF]
We analyze the role of forward-looking indicators, like the IFO business climate indicator and asset prices, in German monetary transmission. We show that the use of both the IFO indicator and asset prices improves the performance and interpretation of a
Elmer Sterken
core
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Editorial: Observational Methodology in Sport: Performance Key Elements
Frontiers in Psychology, 2020 Daniel Barreira +3 more
doaj +1 more source
An Assessment of Telecommunications Regulation Performance in the European Union [PDF]
We assess the performance of National Regulatory Authorities across 16 EU countries regarding economic regulation in telecommunications sector, by constructing a so-called Composite Regulatory Performance Indicator for regulatory aspects such as ...
Antonio Afonso, Carla Scaglioni
core
UK economic performance since 1997: growth, productivity and jobs [PDF]
, 2011 A common view is that the performance of the UK economy between 1997 and 2010 under Labour was very weak and that the current economic problems are a consequence of poor policies in this period.
Corry, Dan +2 more
core
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
A survey on future networks:application scenarios and requirements analysis
Dianxin kexue, 2019 Faced with the severe challenges of today’s network in terms of scalability,mobility,QoS guarantee and manageability,the essential capability requirements of future networks were summarized by analyzing application scenarios of future networks,and the ...
Bin DAI, Yuanyuan CAO, Yijun MO
doaj