Results 81 to 90 of about 2,039,981 (295)

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Comparing performance indicators of obstetric and gynecology ward with expected limits of indicators

open access: yesبیمارستان, 2012
Background: The existed difference statistical indicators is necessary to measure the efficiency of the health organization and as an exact strategy, could be removed the developed problems in heath services sectors.
F Ebadi fard azar   +5 more
doaj  

Trust Performance Indicators and Trust Stress Tests: A Conceptual Proposition for Trustworthy Health Data Spaces

open access: yesInternational Journal of Public Health
The development of trustworthy Health Data Spaces (HDS) is currently in the spotlight of digital health policy. Diverse stakeholders agree on the importance of trust for the adoption and legitimacy of HDS.
Felix Gille   +6 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Developing an AI-Enhanced Enterprise Architecture Model for Strategic Decision-Making in Malaysia’s Railway Industry

open access: yesJOIN: Jurnal Online Informatika
Most developing nations, including Malaysia, still lack a model for the decision-making process that is comprehensive enough to account for a wide variety of potential effects and failures.
Mailasan Jayakrishnan   +2 more
doaj   +1 more source

The Averaged Hausdorff Distances in Multi-Objective Optimization: A Review

open access: yesMathematics, 2019
A brief but comprehensive review of the averaged Hausdorff distances that have recently been introduced as quality indicators in multi-objective optimization problems (MOPs) is presented.
Johan M. Bogoya   +2 more
doaj   +1 more source

Should We Trust in Leading Indicators? Evidence from the Recent Recession [PDF]

open access: yes
The paper analyzes leading indicators for GDP and industrial production in Germany. We focus on the performance of single and pooled leading indicators during the pre-crisis and crisis period using various weighting schemes.
Katja Drechsel, Rolf Scheufele
core  

A novel indicator for kinematic hardening effect quantification in deep drawing simulation [PDF]

open access: yes, 2019
Deep drawing simulation techniques reduce tool design costs and improve tool performance and reliability. In terms of strain hardening, mixed models capturing the kinematic effect are sometimes more accurate than isotropic models.
Brosius, Alexander   +2 more
core  

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Neural Component Analysis for Key Performance Indicator Monitoring. [PDF]

open access: yesACS Omega, 2022
Li Z   +5 more
europepmc   +1 more source

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