Results 111 to 120 of about 2,172,465 (273)
2005 Arts Education Performance Indicators Report [PDF]
, 2005 The mission of Arts for All: Los Angeles County Regional Blueprint for Arts Education is to establish sequential K-12 arts education in each of the 80 school districts in Los Angeles County and the Los Angeles County Office of Education (LACOE ...
core
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
EconomiesReflecting the shift from purely quantitative economic growth to broader socio-environmental sustainability, this study proposes a framework for assessing sustainable development (SD) by integrating Maslow’s hierarchy of needs with Bossel’s ...
Panagiotis Panagiotopoulos +5 more
doaj +1 more source
The Reagan Question: Are You Better Off Now Than You Were Eight Years Ago? [PDF]
, 2008 This paper updates Ronald Reagan's famous question during the 1980 presidential election: "Are you better off now than you were four years ago?" by comparing the state of the economy in 2000 and 2008.
Hye Jin Rho, John Schmitt
core +1 more source
FEBS Letters, EarlyView.Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman +2 more
wiley +1 more source
Assessing Performance of Kerman Province`s Hospitals Using Pabon Lasso Diagram between 2008 and 2010
بیمارستان, 2014 Background: A method of performance assessment is required to improve Productivity and reduce hospital costs . Pabon Lasso diagram is known as a tool for performance assessment.
M Mehrolhasani +2 more
doaj
The Lisbon Strategy Targets are presented and assessed as accordingly to the domains of the structural indicators, the common indicators created to measure the progress towards reaching these objectives: Economic performance; Employment; Research ...
Ivan Ungureanu, Clementina +1 more
core
Annual performance indicators of enforced driver behaviours in South Australia, 2007 [PDF]
, 2009 This report was produced to quantify performance indicators for selected enforced driver behaviours (drink driving, drug driving, speeding and restraint use) in South Australia for the calendar year 2007. The level of random breath testing (RBT) in South
Baldock, M. +2 more
core
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source