Results 61 to 70 of about 467,933 (230)

Assessment of performance of services in a tertiary care Neuropsychiatric Institute using Pabon Lasso Model

Asian Journal of Medical Sciences, 2016
Background: The objective of the study to assess optimal utilisation of hospital facilities & evaluate their performance in a tertiary care hospital using Pabon Lasso Model using indicators- bed turnover (BTO), bed occupancy rate (BOR) and average ...
Chandra Bhushan Tripathi
doaj   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

A decision-support methodology for the energy design of sustainable buildings in the early stages

Cogent Engineering, 2019
A holistic approach integrating all aspects of building design directly affected by its energy performance is necessary for supporting decision-making throughout the design process.
Ernesto Velázquez, Denis Bruneau, Zakaria Aketouane, Jean-Pierre Nadeau   +3 more
doaj   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Biallelic Inactivation of NSD1 Associated With Carcinogenesis in Sotos Syndrome

Pediatric Blood &Cancer, EarlyView.
Nicholas A. Borja, Anuja Sule, Katie Ann McMullen, Aditi Dhir, Matthew D. Hall, Heather J. McCrea, Sakir Humayun Gultekin, Mustafa Tekin, Bradley Gampel   +8 more
wiley   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

U-Space Social and Environmental Performance Indicators

Drones
The social potential of Urban Air Mobility (UAM) as a greener and faster transportation system in and around urban environments is indisputable. Nevertheless, the success of UAM introduction and its wide use will strongly depend on acceptance by the ...
Tatjana Krstić Simić, Emir Ganić, Bojana Mirković, Miguel Baena, Ingrid LeGriffon, Cristina Barrado   +5 more
doaj   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

Match Statistics as Predictors of Team’s Performance in Elite competitive Handball. [Estadística del partido como predictor del rendimiento de equipo en el balonmano de élite].

Revista Internacional de Ciencias del Deporte, 2017
The aim of the present study was to identify performance indicators able to predict victory in a handball match. A documental research was carried out based on data from 80 matches from the Men’s Handball World Championship, held in Qatar in 2015.
Gabriel Daza, Ana Andrés, Rafael Tarragó   +2 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source