Results 101 to 110 of about 18,439,231 (382)

Understanding Supply Chain Complexity with Performance Measurement [PDF]

open access: yes, 2009
: Despite the great number of complex systems existing in the real world, complexity is currently a poorly explored topic. In organizational settings, managers regularly apply to complex contexts classical approaches developed for simple systems, just ...
Ashmos   +27 more
core   +1 more source

Interaction vesicles as emerging mediators of host‐pathogen molecular crosstalk and their implications for infection dynamics

open access: yesFEBS Letters, EarlyView.
Interaction extracellular vesicles (iEVs) are hybrid vesicles formed through host‐pathogen communication. They facilitate immune evasion, transfer pathogens' molecules, increase host cell uptake, and enhance virulence. This Perspective article illustrates the multifunctional roles of iEVs and highlights their emerging relevance in infection dynamics ...
Bruna Sabatke   +2 more
wiley   +1 more source

STAT3 expression is reduced in cardiac pericytes in HFpEF and its loss reduces cellular adhesion and induces pericyte senescence

open access: yesFEBS Letters, EarlyView.
Heart failure with preserved ejection fraction (HFpEF) accounts for half of the heart failure cases. It is characterised by microvascular dysfunction, associated with reduced pericyte coverage and diminished STAT3 expression in pericytes. Loss of STAT3 impairs pericyte adhesion, promotes senescence, and activates a pro‐fibrotic gene program.
Leah Rebecca Vanicek   +15 more
wiley   +1 more source

Net promoter score, growth, and profitability of transportation companies

open access: yesInternational Journal of Management and Economics, 2018
Introduced in 2003, net promoter score (NPS) very quickly gained popularity, as a customer loyalty measure, among companies and a part of researchers, due to its simplicity, the ease of interpretation, low costs of calculation, and, overall, its assumed ...
Korneta Piotr
doaj   +1 more source

A methodical approach to performance measurement experiments : measure and measurement specification [PDF]

open access: yes, 1997
This report describes a methodical approach to performance measurement experiments. This approach gives a blueprint for the whole trajectory from the notion of performance measures and how to define them via planning, instrumentation and execution of the
Beijnum, B.J.F. van   +2 more
core   +1 more source

Enhanced Welding Operator Quality Performance Measurement: Work Experience-Integrated Bayesian Prior Determination

open access: yes, 2019
Measurement of operator quality performance has been challenging in the construction fabrication industry. Among various causes, the learning effect is a significant factor, which needs to be incorporated in achieving a reliable operator quality ...
AbouRizk, Simaan M.   +2 more
core   +1 more source

Ion channel function of polycystin‐2/polycystin‐1 heteromer revealed by structure‐guided mutagenesis

open access: yesFEBS Letters, EarlyView.
Mutations in polycystin‐1 (PC1) or polycystin‐2 (PC2) cause autosomal‐dominant polycystic kidney disease (ADPKD). We generated a novel gain‐of‐function PC2/PC1 heteromeric ion channel by mutating pore‐blocking residues. Moreover, we demonstrated that PC2 will preferentially assemble with PC1 to form heteromeric complexes when PC1 is co‐expressed ...
Tobias Staudner   +7 more
wiley   +1 more source

Protonophore activity of short‐chain fatty acids induces their intracellular accumulation and acidification

open access: yesFEBS Letters, EarlyView.
The protonated form of butyrate, as well as other short‐chain fatty acids (SCFAs), is membrane permeable. In acidic extracellular environments, this can lead to intracellular accumulation of SCFAs and cytosolic acidification. This phenomenon will be particularly relevant in acidic environments such as the large intestine or tumor microenvironments ...
Muwei Jiang   +2 more
wiley   +1 more source

Benchmarking the financial performance of local councils in Ireland

open access: yesAdministration, 2016
It was over a quarter of a century ago that information from the financial statements was used to benchmark the efficiency and effectiveness of local government in the US.
Robbins Geraldine   +2 more
doaj   +1 more source

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