Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Joint Sparsity with Different Measurement Matrices
We consider a generalization of the multiple measurement vector (MMV) problem, where the measurement matrices are allowed to differ across measurements.
Bölcskei, Helmut, Heckel, Reinhard
core +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
LDACS1 ranging performance - an analysis of flight measurement results [PDF]
Dmitriy Shutin +3 more
openalex +1 more source
The role of histone modifications in transcription regulation upon DNA damage
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source
Risk performance indexes and measurement systems for mega construction projects
In recent years, interest in and studies on urban regeneration projects have increased. New urban regeneration projects, i.e., redevelopment projects, are being used to help solve the social and economic problems caused by antiquated buildings and ...
Seon-Gyoo Kim
doaj
Rastreando os direcionadores da performance organizacional: uma proposta metodológica
Este artigo tem por objetivo propor uma metodologia para rastrear a seqüência de causalidade entre direcionadores e indicadores de performance dentro de um sistema de avaliação da performance organizacional.
Bruno Henrique Rocha Fernandes
doaj +1 more source
Measurement of Innovative Performance of Selected Economies of the European Union and Switzerland [PDF]
Ingrid Majerová
openalex +1 more source
“Triple Bottom Line” as “Sustainable Corporate Performance”: A Proposition for the Future [PDF]
Based upon a review of corporate performance, corporate financial performance and corporate social performance, we propose that the concept of ―triple bottom line‖ (TBL) as ―sustainable corporate performance‖ (SCP) should consist of three
Fauzi, Hasan +2 more
core
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley +1 more source

