Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
Molecular Oncology, EarlyView.This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
FEATURES OF UNSCENTED KALMAN FILTER PERFORMANCE USING POLAR MEASUREMENTS
Доклады Белорусского государственного университета информатики и радиоэлектроники, 2019 The principle of the unscented transformation and features of Unscented Kalman filter performance using polar measurement is considered. The estimation performance of Extended Kalman filter and Unscented Kalman Filter is compared.
P. A. Khmarski, A. S. Solonar
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Can net energy values be determined from animal performance measurements? A review of factors affecting application of the California Net Energy System. [PDF]
Transl Anim Sci, 2019 Owens FN, Hicks RB.
europepmc +1 more source
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
Impacts of heifer postweaning residual feed intake classification on reproductive and performance measurements of first, second, and third parity Angus beef females. [PDF]
Transl Anim Sci, 2019 Parsons CT +4 more
europepmc +1 more source
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Cell Complexity Impact on Railway 5G Performance: Measurements Along Tallinn-Tartu Corridor. [PDF]
Sensors (Basel)Pilvik R +3 more
europepmc +1 more source
Molecular Oncology, EarlyView.Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
Unified Multi-Abstraction-Level Functional Testing and Performance Measurements for Industrial IoT in Spatially Distributed Narrow Band-Wireless Wide Area Networks. [PDF]
Sensors (Basel)Sebastian E J, Sowieja F, Sikora A.
europepmc +1 more source