Results 111 to 120 of about 1,474,792 (282)

The Role of Performance Metrics in Estimating Market Values of Footballers in Europe's Top Five Leagues

open access: yesPamukkale Spor Bilimleri Dergisi
The transfer economy in football is a multi-billion-dollar industry, where accurate valuation of players is crucial for clubs' financial sustainability and competitive success.
Murat Işık, Mehmet Ali Yalçınkaya
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Vehicle-to-Cyclist Collision Prediction Models by Applying Machine Learning Techniques to Virtual Reality Bicycle Simulator Data

open access: yesApplied Sciences
The study of vulnerable road users (VRUs) behavior is key to designing and optimizing driving assistance systems, such as the autonomous emergency braking (AEB) system. These kinds of devices could help lower the VRU accident rate, which is of particular
Ángel Losada   +5 more
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Machine Learning Models and Applications for Early Detection

open access: yesSensors
From the various perspectives of machine learning (ML) and the multiple models used in this discipline, there is an approach aimed at training models for the early detection (ED) of anomalies. The early detection of anomalies is crucial in multiple areas
Orlando Zapata-Cortes   +3 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

New Forecasting Metrics Evaluated in Prophet, Random Forest, and Long Short-Term Memory Models for Load Forecasting

open access: yesEnergies
Data mining is vital for smart grids because it enhances overall grid efficiency, enabling the analysis of large volumes of data, the optimization of energy distribution, the identification of patterns, and demand forecasting. Several performance metrics,
Prajowal Manandhar   +3 more
doaj   +1 more source

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