Results 21 to 30 of about 809,994 (242)

A Rapid Prediction of Suppressed Vibration in Composite Bridges Equipped with Constrained Layer Damping

Buildings
The vibration characteristics of a composite bridge with constrained layer damping (CLD) were investigated using the wave and finite element method (WFEM), and the effects of the material and geometrical parameters of the CLD on the vibration reduction ...
Quanmin Liu, Weiwang Fu, Lizhong Song, Kui Gao, Peipei Xu   +4 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Experimental and Numerical Investigation on the Bearing Capacity of Axially Compressive Concrete-Filled Steel Tubular Columns with Local Corrosion

Buildings
This study aims to examine the effects of local corrosion on the axial compression performance of concrete-filled steel tubular (CFST) members. Nineteen CFST short columns with local corrosion were designed and fabricated to undergo axial compression ...
Wei Fang, Mengcheng Chen, Qingqing Wen, Hong Huang, Kaicheng Xu, Rui Zhang   +5 more
doaj   +1 more source

An Action-Independent Role for Midfrontal Theta Activity Prior to Error Commission

Frontiers in Human Neuroscience, 2022
Error-related electroencephalographic (EEG) signals have been widely studied concerning the human cognitive capability of differentiating between erroneous and correct actions.
João Estiveira, João Estiveira, Camila Dias, Camila Dias, Diana Costa, Diana Costa, João Castelhano, João Castelhano, Miguel Castelo-Branco, Miguel Castelo-Branco, Miguel Castelo-Branco, Teresa Sousa, Teresa Sousa   +12 more
doaj   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

A 2.5D peridynamic model for turnout rail crack propagation under wheel rolling contact action

Friction
Based on the ordinary state-based peridynamics (OSB PD) theory, a 2.5-dimensional (2.5D) PD model for rail crack propagation in railway turnouts was proposed.
Xiaochuan Ma, Xianghe Wang, Linya Liu, Weibin Yin, Yajie Wang, Qi Zeng   +5 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Cortical microcircuitry of performance monitoring [PDF]

Nature Neuroscience, 2019
The medial frontal cortex enables performance monitoring, indexed by the error-related negativity (ERN) and manifested by performance adaptations. We recorded electroencephalogram over and neural spiking across all layers of the supplementary eye field, an agranular cortical area, in monkeys performing a saccade-countermanding (stop signal) task ...
Amirsaman Sajad, David C. Godlove, Jeffrey D. Schall   +2 more
openaire   +2 more sources

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Automated design framework for excavation retaining structures: Extending IFC standards and integrating BIM with geotechnical simulation

Underground Space
Challenges arise in automate design with building information modeling (BIM) in underground space. Industry foundation classes (IFC) standard lacks detailed entity objects for describing excavation retaining structures and geological information, and ...
Qiwei Wan, Yuyuan Zhu, Haibin Ding, Wentao Hu, Changjie Xu   +4 more
doaj   +1 more source