Results 71 to 80 of about 809,994 (242)

Low-illumination and noisy bridge crack image restoration by deep CNN denoiser and normalized flow module

Scientific Reports
When applying deep learning and image processing techniques for bridge crack detection, the obtained images in real-world scenarios have severe image degradation problem.
Guangying Qiu, Dan Tao, Dequan You, Linming Wu   +3 more
doaj   +1 more source

Failure Mechanism of Rear Drive Shaft in a Modified Pickup Truck

Metals
This paper investigates the failure mechanism of the rear drive shaft in a modified pickup truck which had operated for about 3000 km. The investigation included macroscopic and microscopic evaluation to document the morphologies of the fracture surface,
Zhichao Huang, Jiaxuan Wang, Yihua Hu, Yuqiang Jiang, Yong Xu, Xiongfei Wan   +5 more
doaj   +1 more source

Croatian First Football League: Teams' performance in the championship

Croatian Review of Economic, Business and Social Statistics, 2016
The goal of our research was to use simulation modelling for prediction of the Croatian First Football League seasonal ranking and analyse variation in teams’ performance during a season.
Munđar Dušan, Šimić Diana
doaj   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source

Automated inverse design of asymmetric excavation retaining structures using multiobjective optimization

Journal of Rock Mechanics and Geotechnical Engineering
Conventional pit excavation engineering methods often struggle to manage the complex deformation patterns associated with asymmetric excavations, resulting in significant safety risks and increased project costs.
Qiwei Wan, Changjie Xu, Xiangyu Wang, Haibin Ding, Xiaozhen Fan   +4 more
doaj   +1 more source

Monitoring of circulating tumor DNA allows early detection of disease relapse in patients with operable breast cancer

Molecular Oncology, EarlyView.
Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad, Marie Austdal, Oddmund Nordgård, Gunnar Mellgren, Satu Oltedal, Marie L. Austbø, Ylva H. Vignes, Thomas Helland, Kristin Jonsdottir, Tone H. Lende, Emilius A. M. Janssen, Bjørnar Gilje, Kjersti Tjensvoll, PBCB study group, Gunnar Mellgren, Tone Hoel Lende, Anette Heie, Kristin Viste, Anita Røyneberg Alvheim, Emiel AM Janssen, Kristin Jonsdottir, Ann Cathrine Kroksveen, Thomas Helland, Einar Gudlaugsson, Oddmund Nordgård, Satu Oltedal, Kristin Løge Aanestad, Jan Terje Kvaløy, Kirsten Lode, Kari Britt Hagen, Marie Austdal, Ylva H. Vignes, Siri Tungland Sola, Nina Egeland Amundsen, Finn Magnus Eliassen, Emeritus Ernst A Lien   +35 more
wiley   +1 more source

Research on the Optimal Design of Retaining Piles of a Wide Metro Tunnel Foundation Pit Based on Deformation Control

Buildings
Engineers pay more and more attention to the economic benefits of foundation pit engineering. At present, the optimal design of the foundation pit supporting structure mainly focuses on strength and functional design, and there is no mature theoretical ...
Wancai Zhong, Qiwei Wan, Nan Nie, Haibin Ding, Feng Gao, Changjie Xu   +5 more
doaj   +1 more source

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

Molecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola, Rafael Lopes Goncalves, Marin Truchi, Caroline Lacoux, Célia Scribe, Hugo Cadis, Laetitia Guardini, Sophie Bekisz, Marius Ilié, Paul Hofman, Georges Vassaux, Bernard Mari, Roger Rezzonico   +12 more
wiley   +1 more source

Experimental Study of Alkali-Activated Cementitious Materials Using Thermally Activated Red Mud: Effect of the Si/Al Ratio on Fresh and Mechanical Properties

Buildings
Bayer red mud (RM)-based geopolymers are economical and ecofriendly alternatives to cement because of their superior performance. This study investigated alkali-activated cementitious materials by combining RM, fly ash (FA) and slag, and the mixtures ...
Kai Guo, Haifeng Dong, Junyi Zhang, Liqing Zhang, Zhiping Li   +4 more
doaj   +1 more source

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

Molecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone, James Dunford, Eleanor Calcutt, Vicki Gamble, Filiz Senbabaoglu Aksu, Lorena Ligammari, Georgina Wherry, Giorgia Gaeta, John C. Christianson, Adrienne M. Flanagan, Udo Oppermann, Adam P. Cribbs   +11 more
wiley   +1 more source