Results 51 to 60 of about 933 (213)
Molecular Oncology, EarlyView.Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard +5 more
wiley +1 more source
Prism blockchain enabled Internet of Things with deep reinforcement learning
Blockchain: Research and ApplicationsThis paper presents a Deep Reinforcement Learning (DRL) based Internet of Things (IoT)-enabled Prism blockchain. The recent advancements in the field of IoT motivate the development of a secure infrastructure for storing and sharing vast amounts of data.
Divija Swetha Gadiraju, Vaneet Aggarwal
doaj +1 more source
Single-inspiratory quantitative CT nomogram for enhanced PRISm and COPD differentiation: a cross-sectional study with interpretable diagnostic boundaries [PDF]
PeerJBackground Differentiating preserved ratio impaired spirometry (PRISm) from chronic obstructive pulmonary disease (COPD) is challenging. Traditional biphasic CT scans are limited by radiation exposure, while single-inspiratory CT-based deep learning ...
Qi Dai +6 more
doaj +2 more sources
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Molecular Oncology, EarlyView.Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
Jurnal Teknik Industri, 2004 This article described a result of research design of performance measurement system in hotel business with Performance Prism Model. As long as, performance measurement system at hotel X not yet representatived organization performance according to ...
Iwan Vanany, Dian Tanukhidah
doaj
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Teknik, 2012 Sultan Agung Islamic Hospital Semarang is a healthcare institution owned by Yayasan Badan Wakaf SultanAgung. To survive against the competitors, the hospital must have a good performance. Thus, a properperformance measurement system is required to assist
Heru Prastawa +3 more
doaj
RekayasaFertilizer production often faces various performance issues that can affect efficiency and productivity. One of the main problems is the instability in the quality of raw materials, which can result in variations in the quality of the final product ...
Fitriatus Sholeha, Farida Pulansari
doaj +1 more source
Journal of Engineering and Management in Industrial System, 2013 Performance measurement method, Performance Prism, was used to improve performance measurement method in this furniture company. Until now, performance measurement system in this company haven’t represented overall organizational performance since it ...
Sri Widiyawati +2 more
doaj +1 more source
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source