Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Trends in Higher EducationUniversity senior management teams are reacting to an evolving trend of identifying and eliminating institutional racism in universities along the North Atlantic Rim.
David B. Roberts
doaj +1 more source
Coping, Confidence and Alienation: the early experience of trainee teachers in English FE [PDF]
, 2012 This article examines what both in-service and pre-service trainee teachers learn from their early experience of teaching in further education (FE) colleges in England.
Orr, Kevin
core +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Leadership: professional communities of leadership practice in post-compulsory education [PDF]
, 2008 Summary: This is a paper that reviews and outlines the academic basis behind leadership in the post-compulsory setting. Description: Leadership has been for some years a key area of strategic and operational importance in the UK post-compulsory sector -
Jameson, Jill
core
How should we conduct ourselves? Critical realism and Aristotelian teleology : a framework for the development of virtues in pedagogy and curriculum [PDF]
, 2018 This is an Accepted Manuscript of an article published by Taylor & Francis Group in Journal of Critical Realism on 19 June 2018, available online: https://doi.org/10.1080/14767430.2018.1484653.
Sharar, Bushra
core +2 more sources
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
Tactical enacting : a grounded theory : a thesis presented in partial fulfilment of the requirements for the degree of Doctor of Education at Massey University, Manawatū, New Zealand [PDF]
, 2016 This research uses classic grounded theory methodology to produce a grounded theory of tactical enacting. Forty two participants were drawn from the population of learning advisors working in a variety of tertiary education organisations in New Zealand ...
Ross, Catherine
core
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Pouvoir des mots, effet des sorts : quelques réflexions sur l’entrée en action sorcellaire
Sociologies, 2014 The mode of action of witchcraft, so well described by the ethnologist Jeanne Favret-Saada, is based upon the power of enunciation and its performative efficiency.
Laurence Kaufmann
doaj