Results 221 to 230 of about 824,468 (289)

From Angiosome to Woundosome: An Interdisciplinary Approach to Personalized Revascularization in Chronic Limb-Threatening Ischemia. [PDF]

Diagnostics (Basel)
Popitiu MI, Patrone L, Clerici G, Comsa S, Gavrila-Ardelean G, Kundnani NR, Olariu N, Ionac ME.   +7 more
europepmc   +1 more source

ANKS1B in the Nucleus Accumbens Controls Escalated Cocaine Self‐Administration via Regulating CBP‐FoxO3 Complex

Advanced Science, EarlyView.
ANKS1B in the nucleus accumbens plays a critical role in the transition from controlled to escalated cocaine intake. Mechanistically, ANKS1B interacts with CBP to epigenetically suppress FoxO3 through H3K27 acetylation. The ANKS1B‐CBP‐FoxO3 signaling cascade presents a novel theraputic target for the treatment of cocaine addiction.
Liping Yang, Xiaoxuan Wu, Xuan Chen, Chao Peng, Zihang Li, Shumin Gao, Shiqiu Meng, Jing Dong, Dong Wu, Liying Lv, Ying Han, Yanxue Xue, Lin Lu, Jie Shi, Jianfeng Liu, Yan Sun   +15 more
wiley   +1 more source

Short-Term Effects of Optically Induced and Digitally Simulated Myopic Blur on Retinal Perfusion: Insights From Optical Coherence Tomography Angiography. [PDF]

Invest Ophthalmol Vis Sci
Hoseini-Yazdi H, Read SA, Yi F, Alonso-Caneiro D, Collins MJ.   +4 more
europepmc   +1 more source

FGL2‐HDAC11 Drives Immunothrombosis via NETs‐Mediated Endothelial Capillarization in MASLD Fibrosis

Advanced Science, EarlyView.
ABSTRACT Metabolic dysfunction–associated steatotic liver disease (MASLD) is frequently accompanied by hepatic fibrosis and systemic cardiovascular complications; however, the mechanistic interplay between coagulation abnormalities and disease progression remains poorly defined.
Xitang Li, Junjian Hu, Suping Hai, Peng Hu, Wenhui Wu, Qiang Gao, Binghui Yu, Feiyang Xu, Xizhe Zheng, Qianting Guan, Huiling Xiang, Dong Xi, Weiming Yan, Peng Wang, Bin‐hao Zhang, Qin Ning, Xiaojing Wang   +16 more
wiley   +1 more source

Accuracy of electrical impedance tomography to detect perfusion defects in pulmonary embolism. [PDF]

Crit Care
Rodrigues EAP, Pacheco EC, Nakamura MAM, Dos Santos ACC, de Melo JL, Plens GM, Alcala GC, Victor M, Xin Y, Cereda M, Gomes S, Lee HJ, Ribeiro BM, Ianotti RM, Freitas-Filho O, Alves-Jr JL, Berra L, Morais CCA, Bertacchini L, Mlček M, Souza R, Borges JB, Costa ELV, Amato MBP.   +23 more
europepmc   +1 more source

mGluR5 in ECCCK to BLA Circuit Modulates Depressive‐Like Phenotypes through CCK Signaling

Advanced Science, EarlyView.
Dysregulation of mGluR5 and CCK signaling contributes to major depressive disorder, yet circuit‐level mechanisms remain unclear. Here, the ECCCK→BLA pathway is identified as a critical regulator of affective behavior. mGluR5 modulates synaptic function and CCK signaling within this circuit, controlling stress susceptibility and depressive‐like states ...
Muhammad Asim, Huajie Wang, Gao Qianqian, Abdul Waris, Jufang He   +4 more
wiley   +1 more source

Transplantation of older DCD livers in the machine perfusion era: a U.S. cohort study. [PDF]

Transpl Int
Giorgakis E, Ziogas IA, Moris D, Varvoglis DN, Theocharopoulos C, Yoeli D, Adams MA, Barbas AS, Montenovo MI, Chen M, Kapoor S, Calderon E, Moon AM, Deutch-Link S, Shroff H, Shah ND, Fix OK, Barritt AS, Mathur AK, Nydam T, Desai CS, Martins PN, Schegel A.   +22 more
europepmc   +1 more source

Astrocytic Phenotypic Switching in Posterior Piriform Cortex Orchestrates Bone Cancer Pain–Depression Comorbidity via Purinergic–Noradrenergic Signaling

Advanced Science, EarlyView.
Bone cancer pain and depression share a common origin: astrocytic A2‐to‐A1 transition in the posterior piriform cortex. This phenotypic shift disrupts the ATP–adenosine–A2AR–norepinephrine axis, simultaneously driving nociceptive and affective dysfunction.
Jiang‐Ping Liu, Jun‐Han Zhang, Zhi‐Xuan Tan, Wei‐Bing Yan, Ya‐Ru Yuan, Yao Liu, Bing‐Di Wei, Meng‐Qi Ding, Zhuo‐Min Fu, Ying Liu, An‐Qi Wang, Lin Ma, Yong‐Hong Li, Er‐Qing Chai, Chao‐Jun Wei   +14 more
wiley   +1 more source

Microcirculation dysfunction and cardioprotection in cardiac surgery with cardiopulmonary bypass: mechanisms, monitoring, and therapeutic strategies. [PDF]

Front Cardiovasc Med
Zheng C, Muir K, Kaushik H, Yalamanchili K, Zahiri K, Yeo A, Kim J, Sellke FW.   +7 more
europepmc   +1 more source

Perfusion Imaging

Journal of Magnetic Resonance Imaging, 2014
M. Günther
semanticscholar   +1 more source