Results 61 to 70 of about 22,850 (146)

A Novel Perfused Full‐Thickness Human Skin Microphysiological System for Modeling Injury, Regeneration, Tumor Pathophysiology, and Therapeutics Development

Advanced Healthcare Materials, EarlyView.
What if human skin could remain fully alive and functional outside the body for weeks? A New Alternative Method (NAM) based on a vascularized full‐thickness skin microphysiological system achieves precisely this, preserving native vasculature, resident immunity, and metabolic activity for up to three weeks, while faithfully recapitulating radiation ...
Yusuf Surucu, Hamid Malekzadeh, Alexa Rivera Del Rio Hernandez, Naresh Mahajan, Ethan Banks, Dayyan Ur Rahman, José A. Arellano, Katherine S. Yang, Alexey Altman, G.V. Naveen Kumar, Matthew L. Steinhauser, Jeffrey A. Gusenoff, J. Peter Rubin, Asim Ejaz   +13 more
wiley   +1 more source

Gammagrafia de la perfusión cerebral en neurología y neurocirugía

Oncología, 2019
Aunque el cerebro constituye el 2-3% del peso total corporal, sin embargo requiere del 20% del consumo total de oxígeno y del 15% del gasto cardiaco, habiéndose estimado que la corteza cerebral normal presenta un flujo sanguíneo promedio de 50-55 ml/min
René F. Cárdenas, Rosalía Durán de Cárdenas   +1 more
doaj  

Feasibility of simultaneous PET-MR perfusion using a novel cardiac perfusion phantom

European Journal of Hybrid Imaging, 2017
Background PET-MR scanners are beginning to be employed for quantitative myocardial perfusion imaging. In order to examine simultaneous perfusion calculations, this work describes a feasibility study of simultaneous PET-MR of gadolinium-based contrast ...
Jim O’Doherty, Eva Sammut, Paul Schleyer, James Stirling, Muhummad Sohaib Nazir, Paul K. Marsden, Amedeo Chiribiri   +6 more
doaj   +1 more source

A Lightweight, 3D‐Printable, Low‐Cost, “One‐Click” Dorsal Skin Window for High‐Quality Long‐Term Multimodal Subcutaneous Tumor Imaging

Advanced Healthcare Materials, EarlyView.
An innovative, lightweight 3D‐printed skinfold chamber system is presented for long‐term intravital imaging. This affordable, biocompatible platform simplifies surgical implantation and allows high‐resolution, multimodal visualization of the tumor microenvironment for up to four weeks.
Iván Cortés Domínguez, Xabier Morales Urteaga, Maider Esparza, Lucía Grande, Ainhoa Urbiola, Cristina Ederra, Tomas Muñoz Santoro, Beatrice Pinci, Alvaro Teijeira, Carlos Ortiz de Solórzano   +9 more
wiley   +1 more source

Utilidad de la perfusión por arterial spin labeling (ASL) en la evaluación de lesiones cerebrales

Anales de Radiología, México
Objetivo: Evaluar la utilidad de la secuencia arterial spin labeling (ASL) en la evaluación de la perfusión cerebral cuantitativa en el diagnóstico de enfermedades cerebrales neoplásica, vascular e inflamatoria. Método: Estudio observacional, transversal
Ángela A. Sánchez-García, María D. Avila-Perfino, Jaime Bravo-Valle, María G. Gómez-Pérez   +3 more
doaj   +1 more source

Macrophage Membrane‐Camouflaged Nanozyme Microneedles Restore Immunovascular Homeostasis Through SPP1‐ApoE Signaling in Diabetic Wounds

Advanced Healthcare Materials, EarlyView.
Macrophage membrane‐coated Cu/Zn‐MOF nanozyme microneedles (MNs) reprogram the diabetic wound microenvironment through localized, minimally invasive delivery. By suppressing M1‐like macrophage activation while promoting extracellular matrix deposition and angiogenesis, this biomimetic platform accelerates diabetic wound repair.
Qipeng Wu, Yuan Xiong, Li Lu, Han Wang, Hui Hu, Mohammad‐Ali Shahbazi, Guohui Liu, Bobin Mi   +7 more
wiley   +1 more source

A 3D‐Printed Vascular‐Like Perfusion Tumor‐on‐a‐Chip Recapitulates High‐Grade Breast Cancer With in Vivo‐Relevant Drug Resistance

Advanced Healthcare Materials, EarlyView.
A high‐resolution 3D‐printed tumor‐on‐a‐chip platform sustains breast cancer tissues at in vivo–like cell densities through vascular‐like perfusion. This engineered system recapitulates grade‐dependent molecular features and exhibits drug‐resistance profiles that uniquely align with clinically relevant Cmax values.
Geonhui Lee, Bingjie Sun, Nicholas X. Fang, Chunguang Xia   +3 more
wiley   +1 more source

Lonicera japonica‐Derived Nanovesicles Ameliorate Acute Lung Injury by Suppressing Neutrophil Extracellular Traps Formation in Mice

Advanced Healthcare Materials, EarlyView.
(A) Isolation and purification of LDNVs. (B) Establishment of the ALI model and LDNVs delivery. (C) Therapeutic mechanisms of LDNVs in treating ALI. This scheme figure was drawn by Figdraw, ID: IUIIO21222. ABSTRACT Acute lung injury (ALI) is a lethal respiratory disease.
Xi Lin, Jian Lin, Yezi Zhang, Xinyan Zhang, Xinghua Liu, Hongying Cao, Huan Shen, Jianming Liang, Zhenhua Dai, Siyuan Xu, Xingdong Lin   +10 more
wiley   +1 more source

The established chest MRI score for cystic fibrosis can be applied to contrast agent-free matrix pencil decomposition functional MRI: a multireader analysis

Frontiers in Medicine
BackgroundEstablished morpho-functional chest magnetic resonance imaging (MRI) detects abnormalities in lung morphology and perfusion in people with cystic fibrosis (pwCF) using a dedicated scoring system.
Eva Steinke, Eva Steinke, Eva Steinke, Eva Steinke, Grzegorz Bauman, Grzegorz Bauman, Ingo G. Steffen, Isabel T. Schobert, Stephanie Thee, Stephanie Thee, Zulfiya Syunyaeva, Jobst Roehmel, Jobst Roehmel, Jobst Roehmel, Helena Posch, Ute L. Fahlenkamp, Carolin Scale, Simon Veldhoen, Oliver Bieri, Oliver Bieri, Mark O. Wielpütz, Mark O. Wielpütz, Mark O. Wielpütz, Mark O. Wielpütz, Marcus A. Mall, Marcus A. Mall, Marcus A. Mall, Marcus A. Mall, Mirjam Stahl, Mirjam Stahl, Mirjam Stahl, Mirjam Stahl, Felix Doellinger   +32 more
doaj   +1 more source

Isolation of Mouse Hepatocytes for Transplantation: A Comparison between Antegrade and Retrograde Liver Perfusion

Cell Transplantation, 2007
We compared antegrade with retrograde liver perfusion when isolating mouse hepatocytes for hepatocyte transplantation. Male mouse hepatocytes were isolated by different perfusion methods and transplanted into the spleen of congeneic female mice ...
Zhaohui Yin, Ewa C. S. Ellis, Greg Nowak
doaj   +1 more source