Results 151 to 160 of about 265,011 (250)

Evaluación de la perfusión de colgajos mediante indocianina verde

, 2018
Resumen Introducción y Objetivo La indocianina verde (ICG) es un colorante que se emplea junto con cámaras de infrarrojo cercano (NIR) portátiles para la evaluación de la perfusión tisular.
Otormín,Gabriel, Novello,Gabriela, Juri,Héctor José, Gambini,Juan Pablo   +3 more
core  

CXCL10/SLC11A1 Axis Exacerbates Septic Liver Injury by Regulating Neutrophil Extracellular Traps Formation to Drive Macrophage Pro‑Inflammatory Polarization

Advanced Science, EarlyView.
In sepsis‐induced liver injury, marked neutrophil infiltration correlates with disease severity. Neutrophil SLC11A1 drives intracellular Fe2+ and ROS via the Fenton reaction, promoting NETs formation. Hepatocyte‐derived CXCL10 recruits neutrophils and activates the JAK/STAT1/SLC11A1 axis, enhancing NETs‐mediated inflammation.
Haiping Lin, Shicong Zheng, Pei Song, Jie Chang, Zewei Chen, Cang Li, Min Yu, Lude Wang, Shian Yu   +8 more
wiley   +1 more source

Cost of Quality of Life in Advanced Parkinson's Disease: Efficient Strategies for Disease Assessment. [PDF]

Rev Neurol
García-Agua Soler N, García Trujillo L, García-Ruiz AJ.   +2 more
europepmc   +1 more source

RPLP2 Mediates the Beneficial Effects of Exercise on Stress Resistance Through Muscle–Brain Communication

Advanced Science, EarlyView.
A novel exercise‐inducible myokine acidic ribosomal protein P2 (RPLP2), initially identified from human trials, is presented here, whose circulating levels negatively correlate with clinical anxiety severity. Muscle‐derived RPLP2 enhances hippocampal ribosomal assembly and adult neurogenesis to rescue stress‐induced anxiety deficits.
Peiyu Luo, Wei Wu, Huan Peng, Dan He, Yuxi Guo, Boyue Zhao, Xiaodan Wang, Li Ma, Yuhang Qin, Yifang Zhai, Lixia Zhuo, Ying Zhang, Yijie Guo, Linlin Jing, Fangyao Chen, Erfei Zhang, Wei Wang, Xiancang Ma, Yan Li   +18 more
wiley   +1 more source

Bridging the gap: molecular mechanisms, regional activity and connectivity in headache disorders. [PDF]

Brain
Kollenburg L, Kurt E, Mulleners W, Arnts H, Robinson CL, Poelen J, Meier K, Dominguez M, Ashina S, Vissers K.   +9 more
europepmc   +1 more source

Isquemia y necrosis escrotal asociada al uso de terlipresina en perfusión continua.

Resumen El síndrome hepatorenal (SHR) se caracteriza por la presencia de una insuficiencia renal reversible que ocurre en pacientes con enfermedad hepática crónica grave, especialmente cirrosis avanzada.
BAIXERAS-MUÑOZ,A, SUÑER-BARRIGA,H, PLO-SECO,I, ESTEVE-PITARCH,E   +3 more
core  

EphB1‐Mediated Transient Blood‐Brain Barrier Opening Facilitates a Ferritin‐Based Nanotherapeutic for Alzheimer's Disease

Advanced Science, EarlyView.
We constructed a brain‐targeted AFn‐DPZ nanodrug delivery system and identified EphB1 as its receptor on the blood‐brain barrier (BBB). This system facilitates drug transport across the BBB and thereby ameliorates cognitive impairment in Alzheimer's disease.
Shilin Wen, Jingjing Gao, Zhixian Wang, Qiumin Ma, Xiao‐Ling Xu, Jianer Chen   +5 more
wiley   +1 more source

Coronary Artery Disease and Chronic Kidney Disease: A Tale of Two Organs. [PDF]

Arq Bras Cardiol
Kranjec I.
europepmc   +1 more source

Unraveling Bone‐Skin Crosstalk Enables miRNA Nanoformulation for Cutaneous Neurovascular Reconstruction in Diabetic Mice

Advanced Science, EarlyView.
This study unravels that bone fracture accelerates diabetic wound healing by releasing exosomal microRNA (miR‐130b‐3p). To mimic this bone‐skin crosstalk, we engineered a self‐assembling agomir‐130b‐3p nanocomplex. Delivered via a photocrosslinkable hydrogel, this bio‐inspired therapy provides sustained localized agomir release.
Tao Shen, Hongdou Shen, Weiyue Wu, Zhuoying Jiang, Bin Liu, Yansi Xian, Rui Peng, An Yan, Yu Ben, Yong Shi, Xiang Chen, Baosheng Guo, Qing Jiang, Weijun Wang, Pingqiang Cai   +14 more
wiley   +1 more source

Mixed shock: from pathophysiology to clinical practice. [PDF]

Arch Peru Cardiol Cir Cardiovasc
Cagide AM, Bluro IM, Arias AM, Pellegrini MN, Iroulart JM.   +4 more
europepmc   +1 more source