BLOC: Buildable and Linkable Organ on a Chip
We developed a “Buildable and Linkable Organ on a Chip” (BLOC) that can construct diverse microphysiological systems (MPSs). The BLOC is standardized to the same size and has one of the functions of “Culture,” “Control,” or “Analysis.” Users can freely configure various MPSs, including developing perfusion, cytotoxicity analysis, and biochemical ...
Yusuke Kimura +7 more
wiley +1 more source
Hydrogel Confinement Strategies for 3D Cell Culture in Microfluidic Systems
Hydrogel confinement structures are key to organizing 3D cell cultures in microfluidic devices. This review classifies five structural strategies (micropillar, phaseguide, porous membrane, stepped‐height, and support‐free) and examines their trade‐offs alongside fabrication methods.
Soohyun Kim, Min Seok Lee, Sung Kyun Lee
wiley +1 more source
Machine perfusion for liver transplantation: opportunities and challenges for the next generation of transplant surgeons. [PDF]
Mullens CL, Shanmugarajah K, Wakam GK.
europepmc +1 more source
This review explores the integration of microfluidic technology with organoid systems as an innovative platform for studying menopausea complex multi‐organ condition. By enabling precise simulation of inter‐organ communication and hormone responses, microfluidic organoids offer a physiologically relevant model for investigating menopausal syndrome and ...
Qianyi Zhang +4 more
wiley +1 more source
Free Arterialized Venous Sural Nerve Flap for Complex Traumatic Tibial Nerve Injury. [PDF]
Sorenson TJ +6 more
europepmc +1 more source
Non‐Invasive Multidimensional Capacitive Sensing for In Vivo Traumatic Brain Injury Monitoring
Single‐electrode, multidimensional capacitive sensors noninvasively assess cerebral autoregulation and compliance for traumatic brain injury monitoring. ABSTRACT Traumatic brain injury (TBI) is a major cause of death and disability, but invasive intracranial pressure (ICP) monitoring is risky, and current non‐invasive methods lack the resolution and ...
Shawn Kim +8 more
wiley +1 more source
Perfusion stability in acute stroke: An observational study exploiting repeated CTP imaging. [PDF]
Rau A +4 more
europepmc +1 more source
An Accessible Microfluidic Platform for the Generation of Polarized Brain Organoids
This study presents an accessible double‐gradient microfluidic device that enables controlled morphogen delivery and spatially polarized differentiation in brain organoids. By integrating a pump‐free design and stable fabrication method, the platform generates dorsal–ventral neuronal asymmetry, offering a reproducible and versatile approach to model ...
Daniel Pérez‐Calixto +6 more
wiley +1 more source
Combined Anatomic and Functional Testing Identifies Patients With Obstructive Coronary Artery Disease Who Benefit From Revascularization. [PDF]
Pedersen OB +8 more
europepmc +1 more source

