Validation of quantitative perfusion cardiovascular magnetic resonance employing deconvolution techniques with Tofts, modified-Tofts, and Fermi function models against <sup>15</sup>O-water positron emission tomography. [PDF]
Takafuji M +12 more
europepmc +1 more source
Circular RNA PTPN4 Contributes to Blood‐Brain Barrier Disruption during Early Epileptogenesis
Epileptic condition induces CircPTPN4 upregulation, which promotes ECE‐1 expression through competitive sequestration of miR‐145a‐5p. The elevated ECE‐1 catalyzes the ET‐1 production, leading to p38/MAPK pathway activation and subsequent downregulation of tight junction protein expression. This cascade results in increased BBB permeability and enhanced
Jiurong Yang +16 more
wiley +1 more source
The SPECTACLE Study: A Multicenter, Prospective, Single-Arm Trial Evaluating Quantitative Blood Flow Assessment Using SPY-QP Software in Minimally Invasive Rectal Cancer Surgery. [PDF]
Hamabe A +15 more
europepmc +1 more source
This study investigates how ischemia‐free liver transplantation (IFLT) shapes both local and systemic immune responses compared with conventional liver transplantation (CLT). Our findings demonstrate that IFLT confers significant immunological protection by attenuating the STAT3‐HIF‐1α axis and enhancing the Heme‐HMOX1 pathway, two regulatory networks ...
Tao Luo +40 more
wiley +1 more source
Total outflow facility before and after goniotomy in <i>ex vivo</i> perfusion models for aqueous humor dynamics: effect of periocular tissue. [PDF]
Kallab M +6 more
europepmc +1 more source
Alternative technique using dual source CT imaging for assessment of myocardial perfusion
Amgad S. Abdel-Rahman +4 more
openalex +1 more source
Acute brain injuries are characterized by extensive tissue damage, resulting in debilitating deficits in patients. Despite considerable progress, cell‐based approaches have yet to identify an ideal candidate. This long‐term study explores the use of an untested cell source – human enteric glia – and a non‐invasive administration route – intranasal ...
Nina Colitti +11 more
wiley +1 more source
Microfluidic Chamber Design for Organ-on-a-Chip: A Computational Fluid Dynamics Study of Pillar Geometry and Pulsatile Perfusion. [PDF]
Liao A, Xiong J, Tong Z, Zhou L, Liu J.
europepmc +1 more source

