Results 141 to 150 of about 123,390 (306)

Nanoporous Microelectrodes for Neural Electrophysiology Recordings in Organotypic Culture

Advanced Materials Technologies, EarlyView.
The highly porous microelectrodes have been designed and printed on culture membranes, allowing to record electrophysiological neural activity for rodent brain slices. To keep the biocompatible nanoporous structure, the microelectrodes and insulative layer are fabricated on the bottom of culture membranes with only small connector pads added on the top.
Petro Lutsyk, Debjani Goswami, Stephen Worrall, Stuart D. Greenhill   +3 more
wiley   +1 more source

Architecture of an All‐In‐One Microfluidic Platform for Accelerated Cancer Seeding, Enhanced Spheroid Formation, and Dynamic Drug Screening Trials

Advanced Materials Technologies, EarlyView.
An all‐in‐one microfluidic platform consists of two‐layered PDMS channels integrated with a hydrogel microwell array. This platform enables flow‐driven tumor cell capture, enhanced spheroid formation within the microwells, and advective drug testing. ABSTRACT Effective cancer drug screening requires platforms that replicate the physiological complexity
Omar M. Rahman, Shengxi Lan, Dae Kun Hwang   +2 more
wiley   +1 more source

Different optical methods for clinical monitoring of the microcirculation [PDF]

, 2002
Bauer, Andreas, Brügger, Dirk, Christ, Frank   +2 more
core   +1 more source

Perfusion Bioreactor Culture Incorporating Mechanical Confinement Enhances Mesenchymal Stem Cell Extracellular Vesicle Production and Wound Healing Potential

Advanced Materials Technologies, EarlyView.
Scalable manufacturing challenges and limited potency remain two of the most intransigent issues limiting clinical translation of EV therapeutics. Mechanical cues can induce phenotypic changes and increased vesiculation in EV source cells without the use of extraneous reagents, chemicals, and/or cargo, thereby potentially drastically improving the ...
Emily H. Powsner, Raith Nowak, Stephanie M. Kronstadt, Nicholas H. Pirolli, Talia J. Solomon, Kristin Nikolov, William Pieper Holeman, Ian M. Smith, Kimberly M. Stroka, John P. Fisher, Steven M. Jay   +10 more
wiley   +1 more source

Imaging of adult ocular neoplasms on a standard 1.5 Tesla MRI magnet: evaluation by improved diagnostic performance of “anatomical” images through feasible technical innovations, supplemented by quick “functional” data

The Egyptian Journal of Radiology and Nuclear Medicine
Background Ocular neoplasms of adults have low prevalence and are usually diagnosed by different ophthalmological techniques, with or without contrast, and are targeted to small lesions.
Lamyaa Abdel Galil Eissa, Sara Mohamed ElBannan, Hisham Farouk Idriss, Aya Mohammed Abdel Aziz   +3 more
doaj   +1 more source

BLOC: Buildable and Linkable Organ on a Chip

Advanced Materials Technologies, EarlyView.
We developed a “Buildable and Linkable Organ on a Chip” (BLOC) that can construct diverse microphysiological systems (MPSs). The BLOC is standardized to the same size and has one of the functions of “Culture,” “Control,” or “Analysis.” Users can freely configure various MPSs, including developing perfusion, cytotoxicity analysis, and biochemical ...
Yusuke Kimura, Hiroki Hamaguchi, Kotaro Oyama, Tomoko G. Oyama, Atsushi Kimura, Yasuhiro Ohshima, Noriko S. Ishioka, Mitsumasa Taguchi   +7 more
wiley   +1 more source

Two‐Photon Polymerized Microvascular Environments for Multicellular Modeling of the Blood–Brain Tumor Barrier

Advanced Materials Technologies, EarlyView.
Modeling the blood–brain tumor barrier is challenging due to complex interactions between brain microvasculature and glioma cells. We present two‐photon polymerized 3D micro‐porous capillary‐like structures that support endothelial alignment, cytoskeletal organization, and pericyte‐endothelial‐glioma tri‐cultures.
Nastaran Barin, Sayba Z. Chowdhury, Maurice de Wit, Rania Head, Kiki Bals, Erwin Brosens, Marvin M. van Luijn, Hayri E. Balcioglu, Angelo Accardo, Pim J. French   +9 more
wiley   +1 more source

Liquid Metal Sensors for Soft Robots

Advanced Robotics Research, EarlyView.
This review thoroughly reviews liquid metal sensors in soft robots. Their unique material properties like high conductivity and good biocompatibility are analyzed. Working principles are classified, and applications in environmental perception, motion detection, and human—robot interaction are introduced.
Qi Zhang, Nan Li, Yujia Song, Chen Hua, Tangzhen Guan, Yibing Ma, Cai Cheng, Jing Liu   +7 more
wiley   +1 more source

Liver Stiffness Directs Intrahepatic Cholesterol Accumulation Through YAP/TAZ in Metabolic Dysfunction‐Associated Steatotic Liver Disease

Advanced Science, EarlyView.
Liver stiffness promotes intrahepatic cholesterol accumulation by repressing LXRα through YAP/TAZ activation. Stiff matrices impair cholesterol efflux in hepatocytes, while YAP/TAZ deletion restores LXRα activity and prevents cholesterol‐induced fibrosis.
Na Young Lee, Myeung Gi Choi, Ho Jae Ryu, Young Jin Min, Seon Min Kim, Yeonseok Chung, Bo Kyung Koo, Yun Pyo Kang, Won Kim, Ja Hyun Koo   +9 more
wiley   +1 more source