Results 211 to 220 of about 127,254 (333)

Gallium‐Doped MXene Nanozymes Protect Liver Through Multi‐Death Pathway Blockade and Hepatocyte Regeneration

Advanced Science, EarlyView.
This study develops gallium‐doped V2C MXene nanozymes (Ga‐V2C) to treat acetaminophen‐induced liver injury through multi‐death pathway blockade and hepatocyte regeneration. Unlike conventional single‐target therapies like N‐acetylcysteine, Ga‐V2C nanozymes enable oxidative stress suppression, apoptosis, and ferroptosis inhibition, and enhanced ...
Xiaopeng Cai, Jingwen Deng, Liqing Wang, Junjie Su, Dongyi Xian, Yilang Yan, Xinyu Yang, Chuanbin Wu, Tingting Peng, Yuan Ding, Guilan Quan, Weilin Wang, Min Zhou, Chao Lu   +13 more
wiley   +1 more source

Efficacy of coronary computed tomography angiography and its fractional flow reserve in predicting myocardial ischemia in patients with obstructive coronary artery disease with positron emission tomography myocardial perfusion imaging as a reference standard. [PDF]

Quant Imaging Med Surg
Wang T, Liu H, Zhao F, Pang Z, Chen Y, Wang J, Li J.   +6 more
europepmc   +1 more source

Prognostic utility and clinical impact of adenosine stress perfusion CMR scan in patients with known coronary disease [PDF]

, 2011
Vijay Dhakshinamurthy, Foord Rachel, Redha Boubertakh, Roshan Weerackcody, Joyce Wong, Ceri Davies, Mark Westwood, Steffen E. Petersen, Anthony Mathur, Saidi Mohiddin, Neha Sekhri   +10 more
openalex   +1 more source

Bioprinting of Microtissues Within Mechanically Tunable Support Baths to Engineer Anisotropic Musculoskeletal Tissues

Advanced Science, EarlyView.
This study presents a novel 4D bioprinting platform for engineering biomimetic musculoskeletal grafts. By tuning the mechanical properties of support baths, we enhance tissue fusion, collagen alignment, and cell differentiation. Using this strategy, we successfully fabricate scaled‐up, anisotropic tissues such as meniscus, articular cartilage, and ...
Francesca D. Spagnuolo, Gabriela S. Kronemberger, Daniel J. Kelly   +2 more
wiley   +1 more source

Stochastic Nanoscale Biophysical Cues as a Basis for the Induction of Glioblastoma‐Like Transcriptional Programs in Astrocytes

Advanced Science, EarlyView.
Stochastic nanoscale physical cues induce glioblastoma (GBM)‐associated transcriptional traits in naïve astrocytes leading to spontaneous formation of spheroids. Cells within spheroids express activated‐MMP2 and a differential gene expression pattern involving P53 and NOTCH3, providing evidence for a role for changes in brain topography, as observed in
Laurent Starck, Tobias Butelmann, Sabrina Hogan, Melika Sarem, Bernd Heimrich, Ritwick Sawarkar, Marie‐Françoise Ritz, Gregor Hutter, V. Prasad Shastri   +8 more
wiley   +1 more source

Three-dimensional spatiotemporal analysis for the assessment of retinal capillary perfusion using a clinical OCT system. [PDF]

Sci Rep
Chen Y, Song J, Jung H, Tse T, Mok V, Tsang J, Mammo Z, Ju MJ.   +7 more
europepmc   +1 more source

A Cold Stress‐Activated Endocrine Sentinel Chemical Hormone Promotes Insect Survival via Mitochondrial Adaptations Through the Adipokinetic Hormone Receptor

Advanced Science, EarlyView.
Seasonal cold adaptation is vital for insect survival, yet the molecular mechanisms linking diapause to mitochondrial resilience remain largely unresolved. We identify ascaroside C9 (asc‐C9) as a key endocrine signal that enhances diapause survival during cold stress by activating the AKHR–PGC1α–UCP4 axis, thereby driving cold‐induced lipolysis and ...
Jiao Zhou, Junxian Chen, Hongxia Zhang, Lu Guo, Kevin Mai, Elijah Abraham, Dilip V. Prajapati, Yue Chang, Jing Ning, Xinchen Wang, Defeng Li, Dan‐Dan Zhang, Jianghua Sun, Rebecca A. Butcher, Lilin Zhao   +14 more
wiley   +1 more source

Alzheimer's disease diagnosis support for brain perfusion SPECT scans in a real-world clinical cohort

Sofia Michopoulou, Angus Prosser, Neil O’Brien, John Dickson, Matthew Guy, Jessica L. Teeling, Christopher Kipps   +6 more
openalex   +1 more source

Perfusion imaging of skin island flap blood flow by a scanning laser-Doppler technique

, 1995
Frank Arnold, Chufa He, Chiyu Jia, G.W. Cherry   +3 more
openalex   +1 more source

Early Antiangiogenic Activity of Bevacizumab Evaluated by Computed Tomography Perfusion Scan in Patients with Advanced Hepatocellular Carcinoma [PDF]

, 2008
Andrew X. Zhu, Nagaraj-Setty Holalkere, Alona Muzikansky, Kerry Horgan, Dushyant V. Sahani   +4 more
openalex   +1 more source