Hyperglycaemia does not increase perfusion deficits after focal cerebral ischaemia in male Wistar rats [PDF]
, 2018 Background: Hyperglycaemia is associated with a worse outcome in acute ischaemic stroke patients; yet the pathophysiological mechanisms of hyperglycaemia-induced damage are poorly understood.
Dewar, Deborah +5 more
core +1 more source
Tc99m Diphosphonate imaging: Giant cell tumours on MDP scanning
South African Journal of Radiology, 1996 Ten patients with histologically proven giant cell tumour (biopsy) were imaged with 3-phase bone scanning, using 99m Tc-MDP. The perfusion (Phase I) and uptake (Phase III) were compared to the normal contralateral side and the rest of the skeleton was ...
M. M. Sathekge, R. P. Clauss
doaj +1 more source
A dual-time-window protocol to reduce acquisition time of dynamic tau PET imaging using [18F]MK-6240
EJNMMI Research, 2021 Background [18F]MK-6240 is a PET tracer with sub-nanomolar affinity for neurofibrillary tangles. Therefore, tau quantification is possible with [18F]MK-6240 PET/CT scans, and it can be used for assessment of Alzheimer’s disease. However, long acquisition
Guilherme D. Kolinger +7 more
doaj +1 more source
Characteristic cerebral perfusion pattern in neuronal intranuclear inclusion disease
Frontiers in Neuroscience, 2022 BackgroundNeuronal intranuclear inclusion disease (NIID), which pathogenesis remains largely unclear, is a neurodegenerative disease caused by GGC repeat expansion in NOTCH2NLC gene.
Hong-Fei Tai +17 more
doaj +1 more source
High-density speckle contrast optical tomography (SCOT) for three dimensional tomographic imaging of the small animal brain [PDF]
, 2017 High-density speckle contrast optical tomography (SCOT) utilizing tens of thousands of source-detector pairs, was developed for in vivo imaging of blood flow in small animals.
Culver, Joseph P +6 more
core +3 more sources
Annals of Clinical and Translational Neurology, 2023 Objective To investigate the effects of the apolipoprotein E (APOE) gene on oxygen saturation and cerebral perfusion in the early stages of traumatic brain injury (TBI). Methods This study included 136 consecutive TBI patients and 51 healthy individuals.
Xun Lin +9 more
doaj +1 more source
Analyzing the human liver vascular architecture by combining vascular corrosion casting and micro-CT scanning: a feasibility study [PDF]
, 2014 Although a full understanding of the hepatic circulation is one of the keys to successfully perform liver surgery and to elucidate liver pathology, relatively little is known about the functional organization of the liver vasculature.
Casteleyn, Christophe +6 more
core +1 more source
Disease activity and cognition in rheumatoid arthritis : an open label pilot study [PDF]
, 2012 Acknowledgements This work was supported in part by NIHR Newcastle Biomedical Research Centre. Funding for this study was provided by Abbott Laboratories.
Birchall, Daniel +6 more
core +1 more source
Combining Low-dose Perfusion with Dual-energy CT Scanning for Pancreatic Neuroendocrine Tumors
CT Lilun yu yingyong yanjiuObjectives: This study explores the clinical value of one-time, low-dose pancreatic CT perfusion combined with dual-energy scanning for detecting pancreatic neuroendocrine tumors. Methods: We retrospectively analyzed data from 23 patients with surgically
Xiaoying HUANG +5 more
doaj +1 more source
Potential use of oxygen as a metabolic biosensor in combination with T2*-weighted MRI to define the ischemic penumbra [PDF]
, 2008 We describe a novel magnetic resonance imaging technique for detecting metabolism indirectly through changes in oxyhemoglobin:deoxyhemoglobin ratios and T2* signal change during ‘oxygen challenge’ (OC, 5 mins 100% O2). During OC, T2* increase reflects O2
Barrie Condon +14 more
core +1 more source