A dual-time-window protocol to reduce acquisition time of dynamic tau PET imaging using [18F]MK-6240
Background [18F]MK-6240 is a PET tracer with sub-nanomolar affinity for neurofibrillary tangles. Therefore, tau quantification is possible with [18F]MK-6240 PET/CT scans, and it can be used for assessment of Alzheimer’s disease. However, long acquisition
Guilherme D. Kolinger +7 more
doaj +1 more source
Objective To investigate the effects of the apolipoprotein E (APOE) gene on oxygen saturation and cerebral perfusion in the early stages of traumatic brain injury (TBI). Methods This study included 136 consecutive TBI patients and 51 healthy individuals.
Xun Lin +9 more
doaj +1 more source
High-density speckle contrast optical tomography (SCOT) for three dimensional tomographic imaging of the small animal brain [PDF]
High-density speckle contrast optical tomography (SCOT) utilizing tens of thousands of source-detector pairs, was developed for in vivo imaging of blood flow in small animals.
Culver, Joseph P +6 more
core +3 more sources
99mTc-MIBI Lung Scintigraphy in the Assessment of Pulmonary Involvement in Interstitial Lung Disease and Its Comparison With Pulmonary Function Tests and High-Resolution Computed Tomography: A Preliminary Study [PDF]
The differentiation of active inflammatory processes from an inactive form of the disease is of great value in the management of interstitial lung disease (ILD).
Assadi, M. +6 more
core +2 more sources
Hyperglycaemia does not increase perfusion deficits after focal cerebral ischaemia in male Wistar rats [PDF]
Background: Hyperglycaemia is associated with a worse outcome in acute ischaemic stroke patients; yet the pathophysiological mechanisms of hyperglycaemia-induced damage are poorly understood.
Dewar, Deborah +5 more
core +1 more source
Combining Low-dose Perfusion with Dual-energy CT Scanning for Pancreatic Neuroendocrine Tumors
Objectives: This study explores the clinical value of one-time, low-dose pancreatic CT perfusion combined with dual-energy scanning for detecting pancreatic neuroendocrine tumors. Methods: We retrospectively analyzed data from 23 patients with surgically
Xiaoying HUANG +5 more
doaj +1 more source
Disease activity and cognition in rheumatoid arthritis : an open label pilot study [PDF]
Acknowledgements This work was supported in part by NIHR Newcastle Biomedical Research Centre. Funding for this study was provided by Abbott Laboratories.
Birchall, Daniel +6 more
core +1 more source
A New Approach in Risk Stratification by Coronary CT Angiography. [PDF]
For a decade, coronary computed tomographic angiography (CCTA) has been used as a promising noninvasive modality for the assessment of coronary artery disease (CAD) as well as cardiovascular risks.
Budoff, Matthew J, Nakanishi, Rine
core +3 more sources
Potential use of oxygen as a metabolic biosensor in combination with T2*-weighted MRI to define the ischemic penumbra [PDF]
We describe a novel magnetic resonance imaging technique for detecting metabolism indirectly through changes in oxyhemoglobin:deoxyhemoglobin ratios and T2* signal change during ‘oxygen challenge’ (OC, 5 mins 100% O2). During OC, T2* increase reflects O2
Barrie Condon +14 more
core +1 more source
A method was established using a scaffold-bioreactor system to examine the impact pulsatile blood flow has on the decellularized porcine kidney vascular architecture and functionality.
Peter R. Corridon
doaj +1 more source

