A dual-time-window protocol to reduce acquisition time of dynamic tau PET imaging using [18F]MK-6240
EJNMMI Research, 2021 Background [18F]MK-6240 is a PET tracer with sub-nanomolar affinity for neurofibrillary tangles. Therefore, tau quantification is possible with [18F]MK-6240 PET/CT scans, and it can be used for assessment of Alzheimer’s disease. However, long acquisition
Guilherme D. Kolinger +7 more
doaj +1 more source
Characteristic cerebral perfusion pattern in neuronal intranuclear inclusion disease
Frontiers in Neuroscience, 2022 BackgroundNeuronal intranuclear inclusion disease (NIID), which pathogenesis remains largely unclear, is a neurodegenerative disease caused by GGC repeat expansion in NOTCH2NLC gene.
Hong-Fei Tai +17 more
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Annals of Clinical and Translational Neurology, 2023 Objective To investigate the effects of the apolipoprotein E (APOE) gene on oxygen saturation and cerebral perfusion in the early stages of traumatic brain injury (TBI). Methods This study included 136 consecutive TBI patients and 51 healthy individuals.
Xun Lin +9 more
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High-density speckle contrast optical tomography (SCOT) for three dimensional tomographic imaging of the small animal brain [PDF]
, 2017 High-density speckle contrast optical tomography (SCOT) utilizing tens of thousands of source-detector pairs, was developed for in vivo imaging of blood flow in small animals.
Culver, Joseph P +6 more
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Disease activity and cognition in rheumatoid arthritis : an open label pilot study [PDF]
, 2012 Acknowledgements This work was supported in part by NIHR Newcastle Biomedical Research Centre. Funding for this study was provided by Abbott Laboratories.
Birchall, Daniel +6 more
core +1 more source
Potential use of oxygen as a metabolic biosensor in combination with T2*-weighted MRI to define the ischemic penumbra [PDF]
, 2008 We describe a novel magnetic resonance imaging technique for detecting metabolism indirectly through changes in oxyhemoglobin:deoxyhemoglobin ratios and T2* signal change during ‘oxygen challenge’ (OC, 5 mins 100% O2). During OC, T2* increase reflects O2
Barrie Condon +14 more
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Combining Low-dose Perfusion with Dual-energy CT Scanning for Pancreatic Neuroendocrine Tumors
CT Lilun yu yingyong yanjiuObjectives: This study explores the clinical value of one-time, low-dose pancreatic CT perfusion combined with dual-energy scanning for detecting pancreatic neuroendocrine tumors. Methods: We retrospectively analyzed data from 23 patients with surgically
Xiaoying HUANG +5 more
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A New Approach in Risk Stratification by Coronary CT Angiography. [PDF]
, 2014 For a decade, coronary computed tomographic angiography (CCTA) has been used as a promising noninvasive modality for the assessment of coronary artery disease (CAD) as well as cardiovascular risks.
Budoff, Matthew J, Nakanishi, Rine
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Twente Optical Perfusion Camera: system overview and performance for video rate laser Doppler perfusion imaging [PDF]
, 2009 We present the Twente Optical Perfusion Camera (TOPCam), a novel laser Doppler Perfusion Imager based on CMOS technology. The tissue under investigation is illuminated and the resulting dynamic speckle pattern is recorded with a high speed CMOS camera ...
Draijer, Matthijs +3 more
core +13 more sources
An in vivo biosensor for neurotransmitter release and in situ receptor activity. [PDF]
, 2010 Tools from molecular biology, combined with in vivo optical imaging techniques, provide new mechanisms for noninvasively observing brain processes. Current approaches primarily probe cell-based variables, such as cytosolic calcium or membrane potential ...
Griesbeck, Oliver +6 more
core +2 more sources