Results 51 to 60 of about 124,759 (287)

An investigation of the relationship between BOLD and perfusion signal changes during epileptic generalised spike wave activity [PDF]

, 2008
In pathological conditions interpretation of functional magnetic resonance imaging (fMRI) results can be difficult. This is due to a reliance on the assumed coupling between neuronal activity and changes in cerebral blood flow (CBF) and oxygenation.
Carmichael, D.W., Duncan, J.S., Hamandi, K., Laufs, H., Lemieux, L., Thomas, D.L.   +5 more
core   +1 more source

Growth Differentiation Factor 15 Elevation in the Central Nervous System Is Associated With Failure to Thrive in Alexander Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Alexander disease (AxD) is a severe neurodegenerative disorder caused by gain‐of‐function mutations in the gene for GFAP, which lead to protein aggregation and a primary astrocytopathy. Symptoms vary, but failure to thrive (FTT) and frequent emesis are common and cause significant morbidity. Here we investigate GDF15, a member of the
Tracy L. Hagemann, Michelle M. Sonsalla, Cora Luzinski, Fernando Zacahua, David A. Harris, Dudley W. Lamming, Albee Messing   +6 more
wiley   +1 more source

Evaluating the Effect of Injected Dose of 99mTc- MIBI on the Quantitative Parameters of Myocardial Perfusion Imaging

Iranian South Medical Journal, 2022
Background: 99mTc-MIBI cardiac perfusion scanning is recognized as a clinically useful method in evaluating coronary artery disease. By the implementation of new imaging techniques and systems, it seems possible to obtain high-quality images with a lower
Mehdi Haghighatafshar, Reza Fatheazam, Tahereh Firuzyar   +2 more
doaj  

The relative contributions of myocardial perfusion, blood volume and extracellular volume to native T1 and native T2 at rest and during adenosine stress in normal physiology

Journal of Cardiovascular Magnetic Resonance, 2019
Background Both ischemic and non-ischemic heart disease can cause disturbances in the myocardial blood volume (MBV), myocardial perfusion and the myocardial extracellular volume fraction (ECV). Recent studies suggest that native myocardial T1 mapping can
Jannike Nickander, Raquel Themudo, Simon Thalén, Andreas Sigfridsson, Hui Xue, Peter Kellman, Martin Ugander   +6 more
doaj   +1 more source

The Legacy of the TTASAAN Report – Premature Conclusions and Forgotten Promises About SPECT Neuroimaging: A Review of Policy and Practice Part II

Frontiers in Neurology, 2022
Brain perfusion single photon emission computed tomography (SPECT) scans were initially developed in 1970s. A key radiopharmaceutical, hexamethylpropyleneamine oxime (HMPAO), was not stabilized until 1993 and most early SPECT scans were performed on ...
Dan G. Pavel, Dan G. Pavel, Theodore A. Henderson, Theodore A. Henderson, Theodore A. Henderson, Theodore A. Henderson, Theodore A. Henderson, Simon DeBruin, Simon DeBruin, Philip F. Cohen, Philip F. Cohen, Philip F. Cohen   +11 more
doaj   +1 more source

A Comparative Study for 2D and 3D Computer-aided Diagnosis Methods for Solitary Pulmonary Nodules [PDF]

, 2008
Many computer-aided diagnosis (CAD) methods, including 2D and 3D approaches, have been proposed for solitary pulmonary nodules (SPNs). However, the detection and diagnosis of SPNs remain challenging in many clinical circumstances.
Lin, Chen-Liang, Nagurka, Mark L., Wang, Jen-Feng, Wu, Ming-Ting, Yeh, Chinson, Yen, Chen-Wen   +5 more
core   +1 more source

3D Bioprinting of Thick Adipose Tissues with Integrated Vascular Hierarchies

Advanced Functional Materials, Volume 35, Issue 12, March 18, 2025.
An advanced 3D bioprinting technique is used here to create thick adipose tissues with a central, vessel and extensive branching. The construct is made using alginate, gelatin and collagen‐based bioinks. Flow through the complex vessel network is demonstrated as well as its successful integration with a femoral artery following implantation in a rat ...
Idit Goldfracht, Majd Machour, Inbal Michael, Maria Bulatova, Janette Zavin, Shulamit Levenberg   +5 more
wiley   +1 more source

Total-liver-volume perfusion CT using 3-D image fusion to improve detection and characterization of liver metastases [PDF]

, 2008
The purpose of this study was to evaluate the feasibility of a totalliver- volume perfusion CT (CTP) technique for the detection and characterization of livermetastases.
Kuijk, Cornelis van, Meijer, Sybren, Meijerink, Martijn, Tol, Petrousjka van den, Waesberghe, Jan van, Weide, Lineke van der   +5 more
core   +8 more sources

Precise Quantification of Angiogenesis in 3D Biomaterials Using in Vitro CAM Models: Enhancing 3Rs in Research and Minimizing in Vivo Dependency

Advanced Functional Materials, EarlyView.
The study develops elastin–fibrin scaffolds and evaluates angiogenesis using the chorioallantoic membrane (CAM) model. Advanced imaging with confocal microscopy and Indocyanine Green dye enables precise 3D quantification of vascular networks. Findings demonstrate superior microvessel visualization compared to micro‐CT using Microfil and Optiray 350 ...
Ece Melis Er, Martha Patricia Pérez González, Beatriz Gil Garrido, Jasmine Ho, Hae‐Won Kim, Jonathan Campbell Knowles, Jia Hua, Ferdinand Lali, Prasad Sawadkar   +8 more
wiley   +1 more source

A simplified method to correct saturation of arterial input function for cardiac magnetic resonance first-pass perfusion imaging: validation with simultaneously acquired PET

Journal of Cardiovascular Magnetic Resonance, 2023
Background First-pass perfusion imaging in magnetic resonance imaging (MRI) is an established method to measure myocardial blood flow (MBF). An obstacle for accurate quantification of MBF is the saturation of blood pool signal intensity used for arterial
Ran Li, Masoud Edalati, David Muccigrosso, Jeffrey M. C. Lau, Richard Laforest, Pamela K. Woodard, Jie Zheng   +6 more
doaj   +1 more source