Results 31 to 40 of about 12,017 (193)

Pump–probe capabilities at the SPB/SFX instrument of the European XFEL

Journal of Synchrotron Radiation, Volume 29, Issue 5, Page 1273-1283, September 2022., 2022
The pump–probe capabilities at the SPB/SFX instrument of the European XFEL are discussed.Pump–probe experiments at X‐ray free‐electron laser (XFEL) facilities are a powerful tool for studying dynamics at ultrafast and longer timescales. Observing the dynamics in diverse scientific cases requires optical laser systems with a wide range of wavelength ...
Jayanath C. P. Koliyadu, Romain Letrun, Henry J. Kirkwood, Jia Liu, Man Jiang, Moritz Emons, Richard Bean, Valerio Bellucci, Johan Bielecki, Sarlota Birnsteinova, Raphael de Wijn, Thomas Dietze, Juncheng E, Jan Grünert, Daniel Kane, Chan Kim, Yoonhee Kim, Max Lederer, Bradley Manning, Grant Mills, Luis L. Morillo, Nadja Reimers, Dimitrios Rompotis, Adam Round, Marcin Sikorski, Cedric M. S. Takem, Patrik Vagovič, Sandhya Venkatesan, Jinxiong Wang, Ulrike Wegner, Adrian P. Mancuso, Tokushi Sato   +31 more
wiley   +1 more source

AD Informer Set: Chemical tools to facilitate Alzheimer's disease drug discovery

Alzheimer's &Dementia: Translational Research &Clinical Interventions, Volume 8, Issue 1, 2022., 2022
Abstract Introduction The portfolio of novel targets to treat Alzheimer's disease (AD) has been enriched by the Accelerating Medicines Partnership Program for Alzheimer's Disease (AMP AD) program. Methods Publicly available resources, such as literature and databases, enabled a data‐driven effort to identify existing small molecule modulators for many ...
Frances M. Potjewyd, Joel K. Annor‐Gyamfi, Jeffrey Aubé, Shaoyou Chu, Ivie L. Conlon, Kevin J. Frankowski, Shiva K. R. Guduru, Brian P. Hardy, Megan D. Hopkins, Chizuru Kinoshita, Dmitri B. Kireev, Emily R. Mason, Charles T. Moerk, Felix Nwogbo, Kenneth H. Pearce, Timothy I. Richardson, David A. Rogers, Disha M. Soni, Michael Stashko, Xiaodong Wang, Carrow Wells, Timothy M. Willson, Stephen V. Frye, Jessica E. Young, Alison D. Axtman   +24 more
wiley   +1 more source

Use of AD Informer Set compounds to explore validity of novel targets in Alzheimer's disease pathology

Alzheimer's &Dementia: Translational Research &Clinical Interventions, Volume 8, Issue 1, 2022., 2022
Abstract Introduction A chemogenomic set of small molecules with annotated activities and implicated roles in Alzheimer's disease (AD) called the AD Informer Set was recently developed and made available to the AD research community: https://treatad.org/data‐tools/ad‐informer‐set/. Methods Small subsets of AD Informer Set compounds were selected for AD‐
Frances M. Potjewyd, Joel K. Annor‐Gyamfi, Jeffrey Aubé, Shaoyou Chu, Ivie L. Conlon, Kevin J. Frankowski, Shiva K. R. Guduru, Brian P. Hardy, Megan D. Hopkins, Chizuru Kinoshita, Dmitri B. Kireev, Emily R. Mason, Charles T. Moerk, Felix Nwogbo, Kenneth H. Pearce Jr., Timothy I. Richardson, David A. Rogers, Disha M. Soni, Michael Stashko, Xiaodong Wang, Carrow Wells, Timothy M. Willson, Stephen V. Frye, Jessica E. Young, Alison D. Axtman   +24 more
wiley   +1 more source

Prenatal case of Simpson–Golabi–Behmel syndrome with a de novo 370Kb‐sized microdeletion of Xq26.2 compassing partial GPC3 gene and review

Molecular Genetics &Genomic Medicine, Volume 9, Issue 8, August 2021., 2021
In the present report, distinctive prenatal sonographic findings from 13 gestational weeks (such as increased nuchal translucency, cleft lip and palate, heart defect and over growth) led to molecular diagnosis. Single Nucleotide Polymorphism Array (SNP array) revealed a de novo 370Kb‐deletion covering the 5′‐UTR and exon 1 of GPC3 gene, which was ...
Jing Liu, Qin Liu, Shuting Yang, Na Ma, Jialun Pang, Ying Peng, Hui Xi, Zhengjun Jia, Yingchun Luo, Meiping Jiang, Yanling Teng, Wenxian Yu, Zhuo Li, Hua Wang   +13 more
wiley   +1 more source

Planning for a second career

Journal of New Librarianship, 2018
This column details the decision-making process and research that second career librarians conduct as they contemplate a career change.
Paula Pergament
doaj   +1 more source

Non‐invasive prenatal testing for the prenatal screening of sex chromosome aneuploidies: A systematic review and meta‐analysis of diagnostic test accuracy studies

Molecular Genetics &Genomic Medicine, Volume 9, Issue 5, May 2021., 2021
MPSS based‐NIPT can be considered as performant for the detection of 45,X in high‐risk pregnancies, although this result is based on studies that might contain biases. For the other SCAs including 47,XXX, 47,XXY, and 47,XYY, more quality studies are still needed.
Bounhome Soukkhaphone, Carmen Lindsay, Sylvie Langlois, Julian Little, Francois Rousseau, Daniel Reinharz   +5 more
wiley   +1 more source

False‐Positive Maternal Serum Screens in the Second Trimester as Markers of Placentally Mediated Complications Later in Pregnancy: A Systematic Review and Meta‐Analysis

Disease Markers, Volume 2021, Issue 1, 2021., 2021
Background. Multiple‐marker, maternal serum screening (MSS) has been the cornerstone of prenatal diagnosis since the 1980s. While combinations of these markers are used to predict fetal risk of Down syndrome and other genetic conditions, there is some evidence that individual markers may also predict nongenetic pregnancy complications, particularly ...
Christy L. Pylypjuk, Joel Monarrez-Espino, Fabrizia Bamonti   +2 more
wiley   +1 more source

Determination of Apomictic Fruit Set Ratio in Several Romanian Walnut (Juglans regia L.) Cultivars

Notulae Botanicae Horti Agrobotanici Cluj-Napoca, 2012
carried out to determine the ability of apomictic fruit setting in twelve Romanian walnut cultivars. ‘Sibisel 44’, ‘Geoagiu 65’, ‘Germisara’, ‘Muscelean’, ‘Sarmis’, ‘Valcor’, ‘Valmit’, ‘Valrex’, ‘Jupanesti’, ‘Velnita’, ‘Orastie’ and ‘Argesean’ cultivars ...
Sina Niculina COSMULESCU, Mihai BOTU, Gheorghe ACHIM   +2 more
doaj   +1 more source

Spaces for servants and provendarii in Early Medieval Monasteries. The example of the virtual monastery on the Plan of Saint Gall

Bulletin du Centre d’Études Médiévales d’Auxerre, 2015
Der St. Galler Klosterplan stellt ein großes frühmittelalterliches Benediktinerkloster vorwiegend im Grundriss dar. Nach allem was wirwissen, wurde die Tuschzeichnung auf Pergament (ca.
Alfons Zettler
doaj   +1 more source

Participatory Microbiome Research With Hmong and Karen Communities: Lessons Learned

Journal of Participatory Research Methods, 2021
In this brief report, we share lessons learned from the Immigrant Microbiome Project (IMP), a microbiome research study conducted in partnership with the Hmong and Karen communities in Minnesota.
Pajau Vangay, Nancy Yang, Shannon Pergament, Mary Xiong, Bwei Paw, Rodolfo Batres, Dan Knights, Kathleen A. Culhane-Pera   +7 more
doaj   +1 more source