Results 131 to 140 of about 12,440,738 (272)

Exploratory randomized trial of Weissella cibaria CMU and oral microbiome changes in peri implant mucositis

Scientific Reports
The oral microbiome plays an important role in maintaining peri-implant health, and microbial imbalance is a key factor in the development of peri-implant mucositis (PIM).
Hyunji Kim, Sujin Oh, Jin-Sil Hong, Mi-Sun Kang, Hyo-Jung Lee, Kyoung Un Park   +5 more
doaj   +1 more source

Sacral Neural Crest‐Derived Extracellular Vesicles Promote Pelvic Ganglion Repair Through Anti‐Pyroptotic Effects Involving ANXA1–FPR2 Signaling

Advanced Science, EarlyView.
Extracellular vesicles derived from human pluripotent stem cell‐derived sacral neural crest cells promote repair of injured major pelvic ganglia and improve colorectal function. These vesicles reduce oxidative stress and pyroptosis, with ANXA1–FPR2 signaling contributing to their protective effects, and show a favorable therapeutic profile compared ...
Ting Yang, Wenwei Liu, Hufei Wang, Yuxin Wu, Yuanchen Ma, Xiaofeng Wang, Tianxiang Lei, Qiao Tang, Yebohao Zhou, Weiqiang Li, Andy Peng Xiang, Wu Song   +11 more
wiley   +1 more source

Using the Modified Apical Access Technique to Treat Peri-Implant Mucosa Defects: Description of the Technique and Three-Dimensional Quantitative Measurement of Buccal Augmented Tissue

Dentistry Journal
The importance of augmenting the peri-implant soft- and hard-tissue architecture is now widely accepted. However, while most contemporary research supports this premise, clinicians are encountering peri-implant soft tissue defects with increasing ...
Norberto Quispe-López, Tiago Marques, Yasmina Guadilla, Javier Flores-Fraile, Pablo Garrido-Martínez, Javier Montero   +5 more
doaj   +1 more source

Human Engineered Heart Tissues Reproduce Trigger‐ and Substrate‐Driven Mechanisms of Ventricular Tachycardia

Advanced Science, EarlyView.
Engineered heart tissues (EHTs) derived from human iPSCs replicate mechanisms of ventricular tachycardia at the tissue level. Acquired Long‐QT conditions cause early afterdepolarizations, wavebreak, and transient rotors; in contrast, focal cryoinjury forms a stable substrate that supports ongoing reentry.
Matthew Fiedler, Alejandra Vasquez Limeta, Ernesto Reyes Sanchez, Leah Carter, Francisco Altamirano   +4 more
wiley   +1 more source

Perioperative/Periprocedural Antithrombotic Management in Oral Health Procedures. A Prospective Observational Study

Dentistry Journal
Background/Objectives: This paper evaluates the incidence of thrombotic and/or hemorrhagic adverse events within 30 days after oral health procedures (OHPs) in patients taking antithrombotic agents.
María González-Zamora, Nagore Ambrosio, Raquel González, Paula Anguita, Ana Molina, David Herrera, Mariano Sanz, Francisco Marín, María Anguita-Gámez, Raquel Ferrandis, David Vivas, Manuel Anguita, Elena Figuero   +12 more
doaj   +1 more source

In Vivo CRISPR Screen Identifies RPS19 as an Immunotherapy Target in Hepatocellular Carcinoma

Advanced Science, EarlyView.
By employing in vivo CRISPR functional screening, we identify ribosomal protein RPS19 as a pivotal mediator driving immune evasion in hepatocellular carcinoma, wherein tumor‑released RPS19 binds C5aR1 on tumor‑associated macrophages to initiate downstream immunosuppressive signaling; SP94‑peptide‑modified SNPSS nanoparticles deliver Cas9/sgRPS19 ...
Lei He, Duo Yu, Fei Xie, Kaisheng Hou, Zhaozhao Li, Meifang Dai, Jingyi Yun, Haiyan Cao, Yang Xiao, Yueyuan Qiu, Gege Shi, Wangqian Zhang, Shuning Wang, Qiang Hao, Jieyu Zhang, Zhaowei Wang, Yingqi Zhang, Kuo Zhang, Jintao Gu, Haichen Du, Meng Li   +20 more
wiley   +1 more source

Evaluation of the Effectiveness of a Postbiotic in Home Care Maintenance in Patients Affected by Peri-Implant Mucositis

Applied Sciences
Peri-implant mucositis is an inflammatory condition that affects the peri-implant mucosa, without bone involvement. Peri-implant mucositis can include erythema, swelling, and bleeding, and the mucosa can be painful even with the traditional oral hygiene ...
Silvia Sabatini, Carlos Perez-Albacete Martinez, Jessica Bassignani, Carolina Maiorani, Andrea Butera, Andrea Scribante   +5 more
doaj   +1 more source

PIAS3 CircRNA‐Loaded Lipid Nanoparticles Restore ALOX15 SUMOylation to Suppress Cementoblast Ferroptosis and Attenuate Orthodontically Induced Root Resorption

Advanced Science, EarlyView.
Orthodontic compression suppresses PIAS3 expression in cementoblasts, impairing ALOX15 SUMOylation and ubiquitin‐mediated degradation, which leads to ALOX15 accumulation, lipid peroxidation, ferroptosis, and osteoclastogenesis. Local delivery of PIAS3 circRNA‐loaded lipid nanoparticles restores the PIAS3–ALOX15 regulatory pathway, alleviates ...
Yifei Hou, Chongzheng Yan, Xinrui Xu, Zihan Yang, Xinhui Wu, Hongxu Zhao, Xuan Song, Jianing Zhang, Yijing Li, Aohua Yang, Xiamei Lu, Yi Liu   +11 more
wiley   +1 more source

Rational Surface Engineering Reduces Advanced Glycation End‐Product Adsorption and Improves Implant Integration

Advanced Science, EarlyView.
Targeted surface chemical modification prevents the accumulation of advanced glycation end products (AGEs) on implant surfaces, attenuates inflammation and fibrosis, effectively restores angiogenic activity, and improves osseointegration under diabetic conditions.
Thien Ngoc Le, Wenhao Chen, Tengxiao Huang, Tien Thanh Nguyen, Markos Negash Alemie, Xuan Duy Do, Giles Best, Jordan Li, Jitraporn Vongsvivut, Vi‐Khanh Truong, Weiwei Li, Yunpeng Zhao, Richard Bright, Krasimir Vasilev   +13 more
wiley   +1 more source

A Novel Bioactive Component, Efoba, From Aged Garlic Targets CTSC to Suppress NET‐Driven Neuroinflammation and Ameliorate Secondary Brain Injury After Intracerebral Hemorrhage

Advanced Science, EarlyView.
Efoba, a novel bioactive component derived from aged garlic, confers neuroprotection against intracerebral hemorrhage. It acts on microglia to suppress CTSC release, inhibits NET‐mediated neural injury, and blocks pathological microglia‐neutrophil crosstalk. This study provides a highly promising lead compound for hemorrhagic‐stroke therapy.
Junjun Meng, Jianhua Wang, Tao Zhang, Xiaofan Fan, Jinxiu Guo, Shiyuan Zhao, Wenxue Sun, Pei Jiang   +7 more
wiley   +1 more source