Results 141 to 150 of about 1,201,019 (394)

A Biologically Informed Vision‐Guided Framework for Interpretable T Cell Receptor–Epitope Binding Prediction

open access: yesAdvanced Science, EarlyView.
Integrating hierarchical physicochemical features via a bio‐inspired design, the DAISY framework robustly predicts T‐cell receptor binding, significantly outperforming state‐of‐the‐art models on unseen epitopes. It uniquely offers visual interpretability via Score‐CAM visualizations and profound clinical relevance, correlating with T‐cell expansion ...
Yajing Yuan   +9 more
wiley   +1 more source

Comparison of marginal bone loss between internal- and external-connection dental implants in posterior areas without periodontal or peri-implant disease [PDF]

open access: hybrid, 2018
Dae‐Hyun Kim   +8 more
openalex   +1 more source

Indentifying human capital externalities: Theory with an application to US cities [PDF]

open access: yes
The identification of aggregate human capital externalities is still not fully understood. The existing (Mincerian) approach confounds positive externalities with wage changes due to a downward sloping demand curve for human capital.
Antonio Ciccone, Giovanni Peri
core  

Epidemiology and risk factors of peri‐implantitis: A systematic review

open access: yesJournal of Periodontal Research, 2018
The purpose of this systematic review and meta-analysis was to assess the prevalence, incidence and risk factors of peri-implantitis in the current literature. An electronic search was performed to identify publications from January 1980 until March 2016
H. Dreyer   +8 more
semanticscholar   +1 more source

Injectable and In Situ Hydration‐Reinforced Hybrid Bone Cements for Accelerated Bone Regeneration

open access: yesAdvanced Science, EarlyView.
To enable minimally invasive bone defect repair, an injectable and hydration‐reinforced bone cement (L‐PEGS/CPC) is designed through biomimetic reconstruction. The hydrophilic L‐PEGS organic phase provides abundant nucleation sites, synergizing with its porous architecture to accelerate CPC hydration, thereby endowing the composite with exceptional ...
Xing Chen   +7 more
wiley   +1 more source

The International Dynamics of R&D and Innovation in the Short and in the Long Run [PDF]

open access: yes
In this paper we estimate the dynamic relationship between employment in R&D and generation of knowledge as measured by patent applications across OECD countries.
Giovanni Peri, Laura Bottazzi
core  

Immunomodulatory Hydrogel Coating with SeNPs and Lithium Silicate Synergistically Promotes Osseointegration and Prevents Infection on Titanium Implants

open access: yesAdvanced Science, EarlyView.
This study introduces a multifunctional hydrogel coating (Lap‐CMCSMA/GelMA@SeNPs) that scavenges ROS, modulates immune responses, and shows strong antibacterial activity. It effectively restores the peri‐implant microenvironment. The coating exhibits excellent biocompatibility and promotes osteogenic differentiation.
Su Jiang   +7 more
wiley   +1 more source

Improved therapeutic consistency and efficacy of CD317+ MSCs through stabilizing TSG6 by PTX3

open access: yesStem Cell Research & Therapy
Background Previously, we have demonstrated that the batch variations of human platelet lysate (conventional MSC expansion medium) induce MSC heterogeneity and therapeutic inconsistency.
Shaoquan Shi   +8 more
doaj   +1 more source

The Supply Chains of Organic Products: An Empirical Analysis of the Processing Sector in Six EU Mediterranean Regions [PDF]

open access: yes
The paper analyses the characteristics of the processing sector of organic products and the relationships with agriculture and retailing sector in six EU Nuts II regions: Lombardy and Tuscany for Italy, Rhone-Alpes and Paca for France, Catalunya and ...
Banterle, Alessandro, Peri, Massimo
core   +1 more source

Flipping the Switch: MeCP2‐Mediated Lactylation Rewires Microglial Metabolism and Inflammation via the HK2/mTOR Axis in Poststroke Neuroinflammation

open access: yesAdvanced Science, EarlyView.
Stroke‐induced lactate accumulation promotes p300‐mediated lactylation of methyl‐CpG binding protein 2 (MeCP2) at lysine 210, which reprograms microglial metabolism toward glycolysis and activates the hexokinase 2 (HK2)/mTOR axis. This cascade promotes proinflammatory responses and impairs neurofunctional outcomes.
Zengyu Zhang   +12 more
wiley   +1 more source

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