Results 161 to 170 of about 1,054,026 (353)

Targeting WTAP/ROR1/WNT5A‐Mediated Crosstalk Between Glioma Stem Cells and Macrophages to Normalize Tumor Vasculature and Enhance Chemotherapy

Advanced Science, EarlyView.
In hypoxic microenvironment, WNT5A is predominantly secreted by tumor‐associated macrophages. Hypoxia‐induced WTAP mediates ROR1 stability by m6A modifications in a HuR‐dependent manner in Glioma stem cells (GSCs). WNT5A activates the WNT pathway via ROR1 binding on GSCs, driving glioma‐derived endothelial cells (GDECs) differentiation.
Xiaoyong Chen, Bo Pang, Yun Liu, Jiangwei Wang, Lanhui Zheng, Yuzhou Chang, Yingxuan Sun, Haoyuan Sun, Huiyuan Chen, Jiawei Cai, Zanyi Wu, Qing Chang, Yongzhi Wang, Dezhi Kang, Tao Jiang, Ruichao Chai   +15 more
wiley   +1 more source

Upper Cambrian to Upper Ordovician peri-Gondwanan Island arc activity in the Victoria Lake Supergroup, Central Newfoundland: Tectonic development of the northern Ganderian margin [PDF]

, 2007
A Zagorevski, Cees R. van Staal, V J McNicoll, N Rogers   +3 more
openalex   +1 more source

Can Peri-Surgical Electroacupuncture Relieve Immunity Suppression? A Pilot Study in Dogs

, 2023
Vanessa Rabbogliatti, Federica Alessandra Brioschi, A. Pecile, V. Bronzo, Valeria Martini, Paola Dall' Ara, Giuliano Ravasio, D. Groppetti   +7 more
openalex   +2 more sources

Cascade Therapy of Periodontitis via Sequential Release of Ribosome‐Targeting Antimicrobial Peptide and Irisin From a Multifunctional MOF‐Based System

Advanced Science, EarlyView.
This study presents a novel strategy for periodontitis treatment by co‐delivering a membrane‐ and ribosome‐targeting antimicrobial peptide GF and Irisin through a pH‐responsive metal‐organic framework. The system enables sequential release, providing rapid antibacterial action, anti‐inflammatory and antioxidative effects, as well as promoting bone ...
Yan Chen, Zheng Xu, Yunmo Xue, Shanshan Liu, Xiang Zhang, Jingyao Guo, Minhui Yao, Yue Liu, Xiaolin Lu, Jieshu Qian, Qian Ma   +10 more
wiley   +1 more source

Schooling Externalities, Technology and Productivity: Theory and Evidence from U.S. States [PDF]

The recent literature on local schooling externalities in the U.S. is rather mixed: positive external effects of average education levels are hardly to be found but, in contrast, positive externalities from the share of college graduates can often be ...
Giovanni Peri, Susana Iranzo
core  

Shorter ovarian stimulation is detrimental to fresh embryo transfer outcomes in PCOS women undergoing GnRH antagonist protocol: a retrospective cohort study

Scientific Reports
Polycystic ovary syndrome (PCOS) is a common endocrine disorder with dysfunctional ovulation affecting female fertility. The purpose of this study was to determine the association between gonadotropin (Gn) duration and in vitro fertilization (IVF ...
Shan Xiao, Su Liu, Ling Hong, Zhiqiang Liu, Rui Jia, Hongzhan Zhang, Meilan Mo, TuRui Yang   +7 more
doaj   +1 more source

Antibiotic resistance of enterobacteria (Escherichia coli, Klebsiella spp. and Salmonella spp) isolated from healthy poultry and pig farms in peri-urban area of Lome, Togo [PDF]

, 2020
Pouwedeou BEDEKELABOU Andre, Talaki Essodina, DOLOU Malibida, DIOUF Adeline, Bada Alambédji Rianatou   +4 more
openalex   +1 more source

Engineering Immune Cell to Counteract Aging and Aging‐Associated Diseases

Advanced Science, EarlyView.
This review highlights a paradigm shift in which advanced immune cell therapies, initially developed for cancer, are now being harnessed to combat aging. By engineering immune cells to selectively clear senescent cells and remodel pro‐inflammatory tissue microenvironments, these strategies offer a novel and powerful approach to delay age‐related ...
Jianhua Guo, Lanjie Lei, Ying Jin, Lan Su, Shumao Cui, Liyun Shi   +5 more
wiley   +1 more source

Innovation and Spillovers: Evidence from European Regions [PDF]

The importance of innovation for the economic performance of industrialized countries has been largely stressed recently by the theoretical and empirical literature.
Giovanni Peri, Laura Bottazzi
core  

Compensatory Interplay Between Clarin‐1 and Clarin‐2 Deafness‐Associated Proteins Governs Phenotypic Variability in Hearing

Advanced Science, EarlyView.
Functional compensation between clarin‐1 and clarin‐2 in cochlear hair cells. Hearing loss associated with CLRN1 mutations shows striking phenotypic variability; however, the underlying mechanisms remain poorly understood. This study reveals that clarin‐1 and clarin‐2 function cooperatively in cochlear hair cells to sustain mechanoelectrical ...
Maureen Wentling, Aïda Yakhlef Sanchez, Nicolas Thelen, Müge Senarisoy, Maria Hogg, Steven Condamine, Andrea Lelli, Emilia Wysocka, Pranav Patni, Sandrine Vitry, Kerem Yasin Yildizhan, Sébastien Le Gal, Sylvie Nouaille, Michael R. Bowl, Marc Thiry, Didier Dulon, Sedigheh Delmaghani, Aziz El‐Amraoui   +17 more
wiley   +1 more source