Results 121 to 130 of about 37,302 (277)

Perianal Basal Cell Carcinoma

, 2015
Basal cell carcinoma (BCC) is the most common non-melanoma skin cancer. Exposure to ultraviolet light is an important risk factor for BCC development and the disorder therefore develops commonly on body areas that are more exposed to sunlight, such as ...
Deniz Arik, Emine Boyuk, Zeynep Nurhan Saracoglu, Isil Bulur   +3 more
core   +1 more source

Delphi consensus: First‐line use of biologics and small molecules in hidradenitis suppurativa

Journal of the European Academy of Dermatology and Venereology, EarlyView.
This Delphi Consensus study identified upgrade criteria for the use of biologics and small molecules as first‐line therapy in hidradenitis suppurativa (HS). European HS experts evaluated 16 clinical scenarios, voting on eligibility for therapy escalation.
Georgios Nikolakis, Erkan Alpsoy, Florian Anzengruber, Matthias Augustin, Falk G. Bechara, Pierre‐André Becherel, Farida Benhadou, Vincenzo Bettoli, Joana Cabete, Raffaele Dante Caposiena Caro, Antonella Di Cesare, Giovanni Damiani, Valentina Dini, Evangelos J. Giamarellos‐Bourboulis, Krisztián Gáspár, Katalin Glasenhardt, Philippe Guillem, Ariela Hafner, Barbara Horvath, John R. Ingram, Vaiva Jarienè, Gregor B. E. Jemec, Alexander Katoulis, Natalia Kirsten, Georgios Kokolakis, Piotr K. Krajewski, Aikaterini I. Liakou, Flavia Manzo Margiotta, Angelo V. Marzano, Antonio Martorell, Lukasz Matusiak, Dillon Mintoff, Alejandro Molina Leyva, Andreas Pinter, Anna Pirogova, Maurizio Podda, Francesca Prignano, Jorge Romani, Marco Romanelli, Elia Rosi, Samed Sahin, Ditte M. L. Saunte, Sylke Schneider‐Burrus, Mariano Suppa, Jacek Szepietowski, Andrea Szegedi, Simon Francis Thomsen, Thrasyvoulos Tzellos, Anastasia Trigoni, Hessel H. Van Der Zee, Kelsey Van Straalen, Skaidra Valiukevičiene, Eva Vilarrasa, Esther von Stebut, Christos C. Zouboulis   +54 more
wiley   +1 more source

Research and Analysis for Cancerous Perianal Disease

, 2017
<p><strong>Objective</strong> To analyze cancerous perianal disease. This study summed up the effective measures for prevention and treatment of perianal cancer patients.
Gui, Tangxue, Hongyu Chen, Jiang, Xiaodong, Taiyu Chen, Chen, Taiyu, Xiaodong Jiang, Tangxue Gui, Chen, Hongyu   +7 more
core   +1 more source

Bimekizumab efficacy using IHS4 outcomes in hidradenitis suppurativa: Results from BE HEARD I and II

Journal of the European Academy of Dermatology and Venereology, EarlyView.
The majority of bimekizumab‐treated patients shifted from severe to mild and moderate IHS4 stages, and nearly 25% achieved an IHS4 of 0 by Week 48. Bimekizumab led to clinically meaningful improvements across IHS4 outcome measures. These data highlight an opportunity to address the need for effective treatments against draining tunnels.
Thrasyvoulos Tzellos, Evangelos J. Giamarellos‐Bourboulis, Kelsey R. van Straalen, Antonio Martorell, Brian Kirby, Afsaneh Alavi, Koremasa Hayama, Saakshi Khattri, Wayne Gulliver, Christopher J. Sayed, Leah Davis, Robert L. Rolleri, Christina Crater, Ingrid Pansar, Jérémy Lambert, Christos C. Zouboulis   +15 more
wiley   +1 more source

Asymptomatic annular perianal sarcoidosis

JAAD Case Reports, 2020
Ijeuru Chikeka, MD, Sameera Husain, MD, Marc E. Grossman, MD   +2 more
doaj   +1 more source

Genomic and proteomic insights into hidradenitis suppurativa

Journal of the European Academy of Dermatology and Venereology, EarlyView.
A dual pathogenic model of HS involving both epithelial dysfunction and systemic inflammation is supported. The HLA‐DRA association hints at autoimmune overlap, but the proteomic signature which is dominated by innate immune mediators favours an autoinflammatory classification, which may guide future therapeutic strategies and patient stratification ...
Maria Argyropoulou, Emmanouil Stylianakis, Isis Ricaño‐Ponce, Nick Keur, Theodora Kanni, Dimitra Stergianou, Mihai G. Netea, Vinod Kumar, Evangelos J. Giamarellos‐Bourboulis   +8 more
wiley   +1 more source

The mode of delivery does not influence the occurrence of post-partum perianal disease flares in patients with inflammatory bowel disease

BMC Gastroenterology
Introduction Perianal disease occurs in up to 34% of inflammatory bowel disease (IBD) patients. An estimated 25% of women will become pregnant after the initial diagnosis, thus introducing the dilemma of whether mode of delivery affects perianal disease.
Ana M. Otero-Piñerio, N. Aykun, M. Maspero, Stefan Holubar, Tracy Hull, Jeremy Lipman, Scott R. Steele, Amy L. Lightner   +7 more
doaj   +1 more source

Perianal Basal Cell Carcinoma

, 2002
Background: A case of basal cell carcinoma (BCC) of the perianal region is reported. This tumor is extremely rare in this location and behaves rather innocently.
Daniel C. Damin, Andre Cartell, Mario A. Rosito, Claudio Tarta, Marcos Weindorfer, Marcos B. Burger, Pedro Gus   +6 more
core   +1 more source

Implementation of a molecular assay for Treponema pallidum detection in the management of syphilis

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Valeria Gaspari, Greta Roncarati, Tiziana Lazzarotto, Claudio Foschi, Antonella Marangoni   +4 more
wiley   +1 more source

Proteomic analysis in hidradenitis suppurativa reveals systemic inflammation in all disease stages

Journal of the European Academy of Dermatology and Venereology, EarlyView.
Proteomic profiling reveals systemic inflammation in patients with hidradenitis suppurativa, even in early disease. Distinct mediators (e.g. TGF‐α, OSM, HGF) are elevated early, whereas others correlate with clinical severity (e.g. IL‐6, VEGF‐A, IL‐17A) or disease duration (e.g.
Lotta Sandelin Francke, Ansam Al‐Bayatti, Hanqian Zhang, Mohammad Alimohammadi, Hans Törmä, Enikö Sonkoly   +5 more
wiley   +1 more source