Results 71 to 80 of about 8,571 (191)

Efficacy and Safety of Mesenchymal Stem Cells in Treatment of Complex Perianal Fistulas: A Meta-Analysis

Stem Cells International, 2020
Complex perianal fistula is a highly debilitating and difficult to treat condition. Local mesenchymal stem cell (MSC) therapy for perianal fistula has shown considerable promise but still remains controversial.
Fang Cheng, Zhong Huang, Zhi Li
doaj   +1 more source

Serious Infection in Crohn's Disease Patients Treated With Ustekinumab: US Food and Drug Administration Active Postmarket Risk Identification and Analysis in the Sentinel Initiative

Clinical Pharmacology &Therapeutics, Volume 119, Issue 6, Page 1514-1521, June 2026.
The U.S. Food and Drug Administration (FDA) used an Active Postmarket Risk Identification and Analysis (ARIA) system to address a safety issue (serious infection) identified during clinical review of an application to market ustekinumab as a treatment for Crohn's disease (CD). FDA used an active‐comparator new‐user cohort design, data from six Sentinel
Joel L. Weissfeld, Geetha S. Iyer, Suna C. Seo, Andrew Giffin, Andrew L. Simon, Sheryl A. Kluberg, Emma R. Hoffman, Jamal T. Jones, Sarah K. Dutcher, Joyce A. Korvick   +9 more
wiley   +1 more source

Added value of Diffusion-Weighted Images & Contrast Enhanced Magnetic Resonance Imaging for the Diagnosis of Perianal Fistula

SVU - International Journal of Medical Sciences
Background: The perianal surgical procedure is aimed at removing all infection sources related to the fistula and its tract, while preserving anal sphincter functions. Various peri-operative risk factors impact perianal fistula recurrence.
Neveen Seif Al-Islam Shaker , Yousra Foud Rashad , Alshimaa Magdy Ammar   +2 more
doaj   +1 more source

The Effect of Ostrich Oil on Pain, Healing, and Recurrence of Chronic Anal Fissure: A Randomized Controlled Double‐Blind Clinical Trial

Health Science Reports, Volume 9, Issue 6, June 2026.
ABSTRACT Background and Aims An anal fissure is a tear in the anal canal below the dentate line, affecting one in five people at some point in their lives. Researchers continuously seek new medications for treating this condition. Ostrich oil has shown anti‐inflammatory and analgesic effects on wounds, as well as angiogenic and re‐epithelialization ...
Masoumeh Taghizadeh, Zahra Kourki Nejad Gharaee, Gholamreza Bazmandegan, Zahra Kamiab, Mohammad Ali Zakeri, Xiao Xu, Inshal Jawed, Mohammadreza Gholamrezapour, Ali Mohammad Madahian   +8 more
wiley   +1 more source

Perianal fistula: retrospective study of surgical treatment of 241 cases

Acta Cirúrgica Brasileira, 1998
Perianal fistula, usually has a criptoglandular etiology, developing from a perianal abscess and communicating the anal mucosa with the perianal skin. The aim of this paper is to study retrospectively 241 cases of perianal fistula (172 men and 69 women ...
Drager Luciano Ferreira, Andrade Miriam Nogueira Barbosa, Conceição Sérgio Alexandre, Cunha-Melo José Renan   +3 more
doaj  

Effectiveness of magnetic resonance imaging in grading of primary perianal fistula and its associated findings in correlation with surgical outcome

The Egyptian Journal of Radiology and Nuclear Medicine, 2017
Perianal fistula is a common disorder with high tendency to recur in spite of satisfactory surgery. Pelvic MRI is the preferable imaging modality for recognition and assessment of perianal fistulas.
Nesreen Mohey, Tamir A. Hassan
doaj   +1 more source

Current Progress in Differentiating Crohn's Disease From Intestinal Tuberculosis

iLABMED, Volume 4, Issue 2, Page 78-90, June 2026.
Currently, there are various methods from different fields used to differentiate Crohn's disease from intestinal tuberculosis (ITB). Endoscopic findings are an important cornerstone. They can be used individually or in combination (models) to demonstrate excellent discriminative ability.
Chuyao Zhang, Xiaoyin Zhang
wiley   +1 more source

Safety and efficacy of weekly adalimumab 80 mg therapy in pediatric Crohn's disease

Journal of Pediatric Gastroenterology and Nutrition, Volume 82, Issue 6, Page 1427-1434, June 2026.
Abstract Objectives Adalimumab is commonly used to induce and maintain remission in pediatric Crohn's disease (CD). However, data on the efficacy and safety of high‐dose adalimumab in this population are limited. This study aimed to evaluate the therapeutic effectiveness and safety of weekly high‐dose adalimumab (80 mg) in pediatric CD patients ...
Eyal Cohen‐Sela, Anat Yerushalmy‐Feler, Firas Rinawi, Esther Orlanski‐Meyer, Raouf Nassar, Ramit Magen‐Rimon, Yael Weintraub, Raanan Shamir, Dror S. Shouval, Manar Matar   +9 more
wiley   +1 more source

Outcome of Modified Ligation of Intersphincteric Fistula Tract Procedure in Patients with Transsphincteric Anal Fistula. [PDF]

Ain-Shams Journal of Surgery
Introduction: Fistula in ano is a common anal disease that is problematic to both the patient and the surgeon.Various treatment modalities have been introduced to treat fistula in ano without compromising anal sphincterfunction.Aim of work: In our study ...
Ahmed Gharib, Adel Abdallah, Ahmed Abbas, Reem Kamel, Ahmed Maarouf   +4 more
doaj   +1 more source

Characteristics and Clinical Outcomes of Patients With Hidradenitis Suppurativa (HS) Treated With Bimekizumab: A Canadian Retrospective Chart Review

JEADV Clinical Practice, Volume 5, Issue 2, Page 627-631, June 2026.
ABSTRACT Background Hidradenitis suppurativa (HS) is a chronic, recurrent inflammatory skin disease characterised by painful nodules, abscesses, and draining and non‐draining tunnels. Currently, there are two biologics approved in Canada for the treatment of moderate‐to‐severe HS, adalimumab (anti‐TNF) and secukinumab (anti‐IL‐17A).
Irina Turchin, Tracey Brown‐Maher, Hélène Veillette, David O. Croitoru, Kyle Cullingham   +4 more
wiley   +1 more source