Role of NOD2 and hepcidin in inflammatory periapical periodontitis [PDF]
The immunological response occurring during periapical inflammation includes expression of nucleotide binding oligomerization domain containing 2 and hepcidin.
Jing Hu +12 more
doaj +5 more sources
The Wnt/β-catenin signaling pathway has a healing ability for periapical periodontitis [PDF]
Various disease-related genes have recently been identified using single nucleotide polymorphisms (SNPs). This study identified disease-related genes by analyzing SNP using genomic DNA isolated from Japanese patients with periapical periodontitis ...
Haruna Naruse +5 more
doaj +3 more sources
Morphological changes of the root apex in anterior teeth with periapical periodontitis: an in-vivo study [PDF]
Introduction The aim was to analyze the morphological changes of root apex in anterior teeth with periapical periodontitis. Methods 32 untreated anterior teeth with periapical periodontitis were enrolled, compared with the healthy contralateral teeth ...
Chen-chen Zhang +6 more
doaj +3 more sources
Metabolome and microbiome of chronic periapical periodontitis in permanent anterior teeth: a pilot study [PDF]
Background Periapical periodontitis is a common oral inflammatory disease that affects periapical tissues and is caused by bacteria in the root canal system.
Yun Huang +6 more
doaj +3 more sources
Evaluating the efficacy of endodontic microsurgery for teeth with an undeveloped root apex and periapical periodontitis after nonsurgical treatment failure [PDF]
Aim To determine the efficacy of endodontic microsurgery for teeth with an undeveloped root apex and periapical periodontitis caused by an abnormal central cusp fracture after failed nonsurgical treatment.
Yumu Tang, Ke Xu, Yumao Chen, Le Lu
doaj +3 more sources
Diagnostic Test Accuracy of Artificial Intelligence in Detecting Periapical Periodontitis on Two-Dimensional Radiographs: A Retrospective Study and Literature Review [PDF]
This study aims to evaluate the diagnostic accuracy of artificial intelligence in detecting apical pathosis on periapical radiographs. A total of twenty anonymized periapical radiographs were retrieved from the database of Poznan University of Medical ...
Julien Issa +5 more
doaj +3 more sources
Resolvin D2 Induces Resolution of Periapical Inflammation and Promotes Healing of Periapical Lesions in Rat Periapical Periodontitis. [PDF]
Periapical periodontitis results from pulpal infection leading to pulpal necrosis and resorption of periapical bone. The current treatment is root canal therapy, which attempts to eliminate infection and necrotic tissue. But, in some cases periapical inflammation doesn't resolve even after treatment.
Siddiqui YD +9 more
europepmc +6 more sources
The effect of root canal treatment and post-crown restorations on stress distribution in teeth with periapical periodontitis: a finite element analysis. [PDF]
Aim To evaluate the effects of root canal treatment (RCT) and post-crown restoration on stress distribution in teeth with periapical bone defects using finite element analysis.
Chen S +15 more
europepmc +2 more sources
Objective: To compare the performance of an AI model with that of experienced radiologists in detecting periapical periodontitis using radiographic images. Methods: Thirty radiographic images (CBCT, panoramic, and periapical) were analyzed by an AI model
Nagareddy B +5 more
europepmc +2 more sources
Osteopontin Promotes Bone Destruction in Periapical Periodontitis by Activating the NF-κB Pathway
Background/Aims: Periapical periodontitis is caused by bacterial infection and results in both one destruction and tooth loss. Osteopontin (OPN) is a secreted phosphorylated glycoprotein that participates in bone metabolism.
Ming Dong +8 more
doaj +2 more sources

