Osteopontin Promotes Bone Destruction in Periapical Periodontitis by Activating the NF-κB Pathway
Background/Aims: Periapical periodontitis is caused by bacterial infection and results in both one destruction and tooth loss. Osteopontin (OPN) is a secreted phosphorylated glycoprotein that participates in bone metabolism.
Ming Dong +8 more
doaj +1 more source
chronic apical periodontitis and birth outcomes: a case-control study [PDF]
Introduction: The relationship between chronic apical periodontitis and adverse pregnancy outcomes is still a matter of debate. The objective of this study was to compare the clinical and radiographic evidence of chronic apical periodontitis in mothers ...
narges farhad mollashahi +3 more
doaj +1 more source
Prevalence and distribution of endodontic treatments and apical periodontitis in an Italian population sample [PDF]
This study was undertaken to investigate for the first time the distribution and prevalence of apical periodontitis and its determinants in an Italian population.
Besharat, Laith Konstantinos +4 more
core +1 more source
Objective To observe the expression of interleukin⁃ 33 (IL⁃33) in macrophages of chronic periapical periodontitis and apical cyst tissue, and to provide a basis for the study of the pathogenesis of IL⁃33 in periapical diseas⁃ es.
DAI Qian, YU Yuanling, HUANG Shiguang
doaj +1 more source
Potential use of human periapical cyst-mesenchymal stem cells (hPCy-MSCs) as a novel stem cell source for regenerative medicine applications [PDF]
Mesenchymal stem cells (MSCs) are attracting growing interest by the scientific community due to their huge regenerative potential. Thus, the plasticity of MSCs strongly suggests the utilization of these cells for regenerative medicine applications.
Codispoti, Bruna +6 more
core +2 more sources
VISTA Blockade Aggravates Bone Loss in Experimental Murine Apical Periodontitis
V-domain Ig suppressor of T cell activation (VISTA) is a novel coinhibitory immune checkpoint molecule that maintains immune homeostasis. The present study explored the role of VISTA in human and murine inflammatory tissues of apical periodontitis (AP ...
Fuhua Yang +5 more
doaj +1 more source
Patient-centered endodontic outcomes: a narrative review. [PDF]
IntroductionRoot canal treatment (RCT) success criteria inform us of the path to bony healing and of prognostic factors, but tell little about how the patient perceives, feels, or values RCT.
Fayazi, Sara +4 more
core +3 more sources
The Presence of Microorganisms in the Granulomatous Tissue of Chronic Periapical Lesions
Apical periodontitis is a sequel to endodontic infection and manifests itself as the host defense response to microbial challenge emanating from the root canal system to the periapical tissue. It is viewed as a dynamic encounter between microbial factors
J. Kováč, D. Kováč
doaj +1 more source
A case report of Parry Romberg Syndrome initially presenting as periodontitis [PDF]
Parry Romberg Syndrome (PRS) is a rare disorder of progressive hemifacial atrophy, involving soft tissues, fat and occasionally bone. It can co-exist with presentations of Morphea.
Bramley +14 more
core +1 more source
Microorganisms in the complex root canal system and the extraradicular regions, including the periapical lesions and extraradicular biofilm may cause root canal treatment failures.
Xiaoqiang Sun +3 more
doaj +1 more source

