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Cytokine Expression in Periapical Granulation Tissue as Assessed by Immunohistochemistry
The aims of this study were to investigate the expression of pro‐inflammatory, anti‐inflammatory and immune‐related cytokines present in periapical lesions. We investigated the expression of cytokines: namely interleukins IL‐2, IL‐4, IL‐6, IL‐10 and interferon‐γ(IFN‐γ) in formalin‐fixed, paraffin‐embedded sections of periapical granulation tissue.
D F Kinane, Keiso Takahashi, D F Lappin
exaly +4 more sources
Human Periapical Granulation Tissue Contains Osteogenic Cells
Bone defects caused by periapical inflammation can be treated and improved by endodontic therapy. However, the mechanism for osseous healing of periapical lesions after root canal treatment is unclear. In this study we examined whether fibroblastic cells from human periapical granulation tissue could produce calcified matrix in vitro.
Aoi Nozu, Akifumi Akamine
exaly +5 more sources
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Guided Tissue Regeneration in Periapical Surgery
Journal of Endodontics, 2010Tissue regeneration by using membrane barriers and bone grafting materials in periapical surgery is an example of tissue engineering technology. Membrane barriers and/or bone grafts are often used to enhance periapical new bone formation. However, the periapical tissues also consist of the periodontal ligament (PDL) and cementum.
Domenico Ricucci +2 more
exaly +3 more sources
Leptin in Dental Pulp and Periapical Tissues: A Narrative Review [PDF]
Leptin is a non-glycosylated 16 kDa protein synthesized mainly in adipose cells. The main function of leptin is to regulate energy homeostasis and weight control in a central manner. There is increasing evidence that leptin also has systemic effects, acting as a link between innate and acquired immune responses.
Victor Sánchez-Margalet +2 more
exaly +6 more sources
Actinomycosis of the periapical tissues
Oral Surgery, Oral Medicine, Oral Pathology, 1968Abstract We have presented a case of anterior mandibular actinomycosis in which the infection led to pulp death. A review of the literature is included, and some comments regarding diagnosis and therapy are made.
P, Kapsimalis, G E, Garrington
openaire +2 more sources
Sodium hypochlorite injection into periapical tissues
Journal of Endodontics, 1989Sodium hypochlorite is a useful adjunct to endodontic therapy but it must be confined to the root canal. A case of periapical injection of hypochlorite with untoward sequellae is presented.
C L, Sabala, S E, Powell
openaire +2 more sources

