Results 91 to 100 of about 53,825 (265)

Defining minimum image quality criteria for common diagnostic point‐of‐care ultrasound images: A position statement of the Society of Hospital Medicine

open access: yesJournal of Hospital Medicine, EarlyView.
Abstract Background Point‐of‐care ultrasound (POCUS) use continues to expand across multiple clinical subspecialties, and the need for standardization of training and quality assurance has become increasingly important. Despite the need for training, there are currently no widely accepted multispecialty criteria to define an acceptable quality POCUS ...
James Anstey   +33 more
wiley   +1 more source

Sample Size of Trials Investigating the Impact of Point‐of‐Care Ultrasound‐Guided Strategies on Patient Outcomes

open access: yesJournal of Ultrasound in Medicine, EarlyView.
Point‐of‐care ultrasound (POCUS) is increasingly utilized for bedside diagnosis and management in diverse clinical contexts. However, the design of randomized controlled trials (RCTs) evaluating the impact of POCUS‐guided strategies on clinical outcomes presents significant challenges.
William Beaubien‐Souligny   +2 more
wiley   +1 more source

Clinical Outcomes of Different Generation EGFR TKIs in Susceptible EGFR‐Mutated Advanced Nonsmall‐Cell Lung Cancer

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) are indicated for advanced lung adenocarcinoma patients harboring susceptible EGFR mutations. The aim of this retrospective study was to compare the effectiveness of different generations of EGFR TKIs.
Chia‐Yu Kuo   +9 more
wiley   +1 more source

The Evolving Landscape of Immunotoxicity: Charting Mechanisms and Future Strategies for Immune Checkpoint Inhibitor Adverse Events

open access: yesMed Research, EarlyView.
ABSTRACT The use of immune checkpoint inhibitors (ICIs) has significantly improved the efficacy of cancer therapy, but their associated immune‐related adverse events (irAEs) can severely compromise treatment safety. This review systematically summarizes the core mechanisms underlying irAEs, which include multi‐organ damage resulting from T‐cell ...
Anqi Lin   +8 more
wiley   +1 more source

Rib Ewing Sarcomas in Children and Young Adults: A Large National Retrospective Series

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background and Purpose Ewing sarcoma (ES) is the most prevalent malignant thoracic tumor in childhood and young adults. This study reports the outcome of a national cohort treated in an international prospective trial for a localized rib ES, with a long follow‐up.
Audrey Claren   +14 more
wiley   +1 more source

Management of Pediatric and Adolescent Rhabdomyosarcoma of the Chest Wall: An Expert Consensus Opinion From the International Soft Tissue Sarcoma Consortium (INSTRuCT)

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT The International Soft‐Tissue Sarcoma Consortium (INSTRuCT) was established as a global partnership among various pediatric soft tissue sarcoma groups, including the Children's Oncology Group (COG), European Pediatric Soft Tissue Sarcoma Group (EpSSG), and Cooperative Weichteilsarkom Studiengruppe (CWS). One of INSTRuCT's primary objectives is
Andreas Schmidt   +8 more
wiley   +1 more source

Diagnosis and Management of Prenatal Hereditary Pyropoikilocytosis

open access: yesPrenatal Diagnosis, EarlyView.
ABSTRACT Hereditary pyropoikilocytosis (HPP) is a severe hemolytic anemia caused by variants in SPTA1, SPTB, and EPB41. These weaken horizontal interactions in the erythrocyte cytoskeleton, causing membrane fragmentation and splenic sequestration. It will readily cause fetal anemia and often hydrops fetalis. Prenatal diagnosis requires first ruling out
Connor Hartzell   +6 more
wiley   +1 more source

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