Results 81 to 90 of about 151,922 (279)
Abstract Aims Amyloid cardiomyopathy is caused by the deposition of light chain (AL) or transthyretin amyloid (ATTR) fibrils, that leads to a restrictive cardiomyopathy, often resulting in heart failure (HF) with preserved or reduced ejection fraction.
Robin Willixhofer+25 more
wiley +1 more source
Immune Checkpoint Inhibitors and Cardiovascular Adverse Events
Abstract In the last years, we assisted to a tremendous increase in therapeutic options for the management of cancers, with immunotherapy at the forefront of this innovation. Immune checkpoint inhibitors (ICIs) have been developed to enhance the activity of the immune system against cancer cells (1) and the number of approvals for ICIs has rapidly ...
Maria Luisa De Perna+4 more
wiley +1 more source
Message in a bottle. The use of chest radiography for diagnosis of pericardial effusion
The diagnosis of pericardial effusion may be elusive, and only diagnosed with echocardiography. Case reports: Here we report the cases of two patients who presented to the emergency centre (EC) with dyspnoea, and their chest X-rays (CXR) revealed the ...
James Foley, Lai Pun Tong, Navin Ramphul
doaj +1 more source
Acute myocarditis according to age: Presentation, management and early outcomes
MIS, multisystem inflammatory syndrome; MRE, myocarditis‐related events (within 30 days included all‐cause death, cardiogenic shock, cardiac arrest, ventricular arrhythmias or complete AV block). Abstract Aims Acute myocarditis (AM) is a rare but severe disease affecting patients of all ages. Large multicentric studies comparing children and adults are
Clément Karsenty+25 more
wiley +1 more source
Background Pericardial effusion (PE) indicates the build-up of fluid within the pericardial sac, which encases the heart. The present study was undertaken to assess the clinical profile, etiology of pericardial effusion and to determine the correlation ...
Nafeez Javed Shaik+3 more
doaj +1 more source
Pulmonary hypertension complicated by pericardial effusion: a single center experience
Background: Pericardial effusion is an independent predictor of mortality in patients with pulmonary arterial hypertension (PAH). However, the management and outcomes of patients with pulmonary hypertension (PH) and pericardial effusion are not well ...
Gregory R. Honeycutt, Zeenat Safdar
doaj +1 more source
Systematic approach to dilated cardiomyopathy diagnosis. Dilated cardiomyopathy is a clinical diagnosis characterized by the presence of left ventricular dilatation and systolic disfunction unexplained by abnormal loading conditions or coronary artery disease.
Kristian Galanti+14 more
wiley +1 more source
Therapeutic targeting of chromatin alterations in leukemia and solid tumors
Abstract Alterations in chromatin conformation and post‐translational modification of histones have become increasingly recognized as critical drivers of cancer development, progression, and therapy resistance. Recent advances in drug development have led to the establishment of several highly selective small molecule inhibitors, several of which are ...
Florian Perner+7 more
wiley +1 more source
BACKGROUND Treatment of malignant pericardial effusion remains controversial, because no randomized controlled trials have been conducted to determine the best approach, and results of retrospective studies have been inconsistent.
C. Labbé, L. Tremblay, Y. Lacasse
semanticscholar +1 more source
Tuberculous pericarditis is a common type of pericarditis, but it is difficult to be diagnosed. The application of combined transesophageal echocardiography, contrast echocardiography, and CT multimodal imaging provides sufficient clinical diagnosis basis and guidance for distinguishing encapsulated pericardial effusion or mass.
Yang Han+5 more
wiley +1 more source